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A#321 - A Diet to Die For - Case Study HWK

Last updated almost 5 years ago
3 questions
Read through the next several slides. Feel free to jot down notes on the science behind the drug and how it works. This will help you answer questions later on.
name of the drug might be important : )
LD50 is the amount of a substance that causes the death of 50% of the group taking it. It is an important part of pharmaceutical testing.
1

write a one or two sentence summary of oxidative phosphorylation

This is a good slide to refer back to - what is measured and what it means when it comes to different experiments.
1

What do you predict will happen here? Write a summarizing statement AND draw out a graph. Use the axes provided. What will happen to the graph when succinate is added to the ADP + P in solution? What would then happen when cyanide is added? You should have 2 lines on the graph - one for oxygen consumed and one for amount of ATP synthesized. I would suggest graphing what happens to amount of ATP synthesized, and then graph O2 consumed.

If you need some help with this graph - think about 1)what are your reactants - if you have them, then you can make ATP - you need ADP + P plus a source of energy (something oxidizeable). 2) If you inhibit part of the ETC, then you reduce the amount of H+ ions, and so what will happen to the amount of ATP produced?
Now draw your graph of ATP production at each of the three pts - when you have ADP + P, when you add succinate, and finally, when you add cyanide. Now repeat the thought process, but for oxygen consumption.
1

What do you predict will happen here? Write a summarizing statement AND draw out a graph. Use the axes provided. What will happen to the graph when succinate is added to the ADP + P in solution? What would then happen when cyanide is added? You should have 2 lines on the graph - one for oxygen consumed and one for amount of ATP synthesized. I would suggest graphing what happens to amount of ATP synthesized, and then graph O2 consumed.

We will continue to work on this Monday in class