Climbing at high altitude can be nauseating, dizzying, and it can kill you. It's cold up there, and let's face it, humans have evolved to live in relatively warm climates. If had we had evolved to live in constant cold, our bodies might have grow thick hair all over, we might store more fat, and our body shape might be rounder and shorter to prevent heat loss. In addition, Denali is one of the highest mountains on Earth. And the higher you climb, the thinner the air is and the harder it is to breathe.