In 1979, friends dared a 29-year-old man in Oregon to swallow a living rough-skinned newt. The man didn’t realize how poisonous roughskinned newts are. A lethal, fast-acting poison called tetrodotoxin (TTX) oozes from their skin. The man swallowed the newt whole and started feeling weak a few minutes later. He described a numb feeling all over his body. His friends tried to take him to a hospital, but he refused. Just 20 minutes later, the man was dead. Of course, the newt the man swallowed died, too. In that particular case, being poisonous didn’t help that individual newt survive. If newts have to be eaten in order to defend themselves, being poisonous doesn’t sound like a very good defense! How is being poisonous—having a high level of TTX poison— an adaptive trait for a rough-skinned newt?