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Laabri

Unit 4: Inheritance and Variation Test

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39 Nsɛmmisa
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1.

Compared with normal hemoglobin, the hemoglobin of a person with sickle cell disease

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2.

The following cross shows two people who are carriers for sickle cell anemia. In this cross, R is the allele for a normal red blood cell, while r is the allele for a sickle, mutated blood cell.

​​What is the chance that an offspring from this cross will be fully affected with sickle cell anemia?

Read the scenario and use the information to help you answer the questions.

Disease Possibilities

A man and woman have decided to have children but are worried about possible genetic diseases. The couple visits a geneticist to determine what the possible risks are for their future children. The couple learns that they are both carriers (heterozygous) for Sickle Cell Disease. Each of them has one recessive allele. In order to have Sickle Cell Disease, you have to have two recessive alleles. The following year, the parents are blessed with a bouncing baby boy!

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3.

Which of the following is the correct genotype of the parents?

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4.

What is the probability (percent chance) that the child will have the same genotype as the parents?

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5.

What is the probability (percent chance) that the child will have Sickle Cell Disease?

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6.

The baby boy goes through his newborn tests and the doctors discover that the boy does have Sickle Cell Disease. What is the child's genotype?

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7.

At the end of Meiosis, how many gametes are produced?

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8.

How many chromosomes does a diploid human cell have?

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9.

Which three of the following may lead to genetic variations?

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10.

The gametes produced at the end of Meiosis are different in chromosome number than other cells in that they have fewer chromosomes. After going through the process of Meiosis, gametes are referred to as

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11.

Based on the pedigree shown below, how is it possible for the daughter to have a curved thumb while the rest of the family has straight thumbs? Straight thumbs are dominant, curved thumbs are recessive.

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12.

The allele for the presence of a white forelock is dominant in Figure 14–1. What is the probability of the couple labeled 2 of having a child with the trait?

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13.

Carefully review the entire image above before answering the question.

Epigenetics has the ability to change phenotypes. Epigenetics is not considered a mutation because

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14.

Mendel's law of segregation occurs during which phase of meiosis?

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15.

What is the role of meiosis in sexual reproduction?

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16.

Gametes are produced by the process of

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17.

Gametes have

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18.

What is shown in the image below?

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19.

If a eukaryotic cell has 20 chromosomes and it undergoes meiosis, how many cells will result, and how many chromosomes will they contain?

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20.

Match the number of each phase in the diagram to the phase of meiosis that is shown.

Draggable itemarrow_right_altCorresponding Item

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Prophase I

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Anaphase II

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Metaphase I

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Metaphase II

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Telophase/cytokinesis II

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Anaphase I

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Interphase

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Prophase II

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21.

What is the process in which DNA makes a copy of itself?

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22.

What is the function of DNA polymerase during replication?

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23.

Why is DNA replication considered semi-conservative?

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24.

True or false: ALL mutations effect the resulting protein

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25.

Which of the following explains why mutations may have no affect on a protein?

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26.

Which of the following mutations is most likely going to have large affects on any proteins made from the gene(s) involved?

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27.

In humans the ability to taste Phenylthiocarbamide (PTC) is dominant. “Tasters” (TT) or (Tt) taste an extremely bitter taste from PTC, while “non-tasters” (tt) do not taste anything.

What are the genotypes of Mr. and Mrs. Jones if they can taste PTC but have a child who is a non-taster?

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28.

In pigs, having erect ears that stick up (E) is dominant to having droopy ears (e).

If a pig has droopy ears what must its genotype be?

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29.

Fill in the missing information for the Punnett square below

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30.

What is the expected genotype ratio of a monohybrid cross (Tt x Tt)?

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31.

What are the possible genotypes of offspring from a cross between two heterozygous parents?

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32.

In horses, having black hair is dominant (B) to having chesnut colored hair (b).

If a homozygous dominant horse is crossed with a chesnut colored horse, then what are the chances they will have a foal (a baby horse) with chesnut colored hair?

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33.

How many males are there?

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34.

How many males have hemophilia?

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35.

How many children did the couple in generation 3 (III) have?

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36.

This pedigree tracks hemophelia in a family. How many of II-2's grandsons have hemophelia?

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37.

The pedigree below tracks the appearance of a recessive trait:

Match each individual on the left with the correct genotype on the right.

  • Sister

  • Brother 2

  • Dad

  • Mom

  • Brother 1

  • Definitely homozygous dominant

  • Definitely heterozygous

  • Definitely homozygous recessive

  • Could be homozygous dominant or heterozygous

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38.

How does the end result of mitosis compare to meiosis? Select ALL that apply.

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39.

Compare the mutated DNA sequence to the original. Identify the mutation as either an insertion, deletion, or substitution, and whether it is a frameshift, missense, nonsense, or silent mutation.

Original DNA Sequence: T A C A C C T T G G C G A C G A C T

Mutated DNA Sequence: T A C A T C T T G G C G A C G A C T