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SickleCellMalariaChiSquare

Posljednje ažuriranje 4 months ago

25

1

1

1

1

1

1

1

1

1

1

1

Pitanje 11

11.

1

Pitanje 12

12.

1

Pitanje 13

13.

1

Pitanje 14

14.

reject null hypothesis - there is a statistically significant difference btw obs and exp - natural selection is acting on the population

1

Pitanje 15

15.

AS genotypes

1

Pitanje 16

16.

1

Pitanje 17

17.

1

Pitanje 18

18.

P < .05

1

Pitanje 19

19.

null is rejected

1

Pitanje 20

20.

SS selected against - likely poor health care

1

Pitanje 21

21.

1

Pitanje 22

22.

1

Pitanje 23

23.

1

Pitanje 24

24.

1

Pitanje 25

25.

Pitanje 1

1.

AA

AS

SS

Pitanje 2

2.

AA

AS

SS

Pitanje 3

3.

AA

AS

SS

Pitanje 4

4.

AA

AS

SS

Pitanje 5

5.

AA

AS

SS

Pitanje 6

6.

AA

AS

SS

Pitanje 7

7.

100%

75%

50%

25%

0%

Pitanje 8

8.

100%

75%

50%

25%

12.5%

0%

Pitanje 9

9.

No - the highlands are dry so less malaria

Pitanje 10

10.

null

The isolated population sampled here is facing selection pressures caused by both limited health care as it relates to sickle cell disease and the introduction of malaria through the Anopheles mosquito, which carries the malaria-causing parasite. Therefore, the deviation of the observed numbers from the expected numbers is larger than it was from the first scenario due to the presence of three selection pressures. First, the sickle cell disease genotype (SS) is strongly selected against; second, the normal (AA) genotype is selected against due to the higher susceptibility to malaria infection. Finally, the data suggest that there is selection for the sickle cell trait (AS) genotype because these individuals do not have sickle cell disease and are more resistant to malaria.