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6 - Immunity and Vaccination

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Last updated almost 5 years ago
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Learning Objectives: I will...
  • review the immune response
  • understand how vaccines work
You will now learn more about the human immune system's response to vaccination by exploring a simulation (click on the link).
As you explore, consider how vaccines help individuals develop specific immunity to infectious diseases.
Only complete the "How Vaccines Work" simulation.
Now view each of the video clips from, "How do vaccines work?" and answer the questions that follow.
Question 1
1.

Question 2
2.

Question 3
3.

Question 4
4.

What is our second line of defense called?

Question 5
5.

Question 6
6.

What system does vaccines trigger?

Question 7
7.

Question 8
8.

Question 9
9.

Question 10
10.

What is are downsides to a live attenuated vaccine?

Question 11
11.

Question 12
12.

Question 13
13.

Since we have our immune system to protect us from disease, why do we still need vaccines and how do they work?

You are aware of B and T cells, special types of white blood cells that help your body to fight off a specific pathogen. They are necessary when the body is fighting off an infection. But what happens to them after the pathogen has been destroyed?
Most B and T cells die after an infection has been brought under control. But some of them survive for many years. They may even survive for a person’s lifetime. These long-lasting B and T cells are called memory cells. They allow the immune system to “remember” the pathogen after the infection is over. If the pathogen invades the body again, the memory cells will start dividing in order to fight the pathogen or disease.
These dividing cells will quickly produce a new army of B or T cells to fight the pathogen. They will begin a faster, stronger attack than the first time the pathogen invaded the body. As a result, the immune system will be able to destroy the pathogen before it can cause an infection. Being able to attack the pathogen in this way is called immunity.
Immunity can also be caused by vaccination. Vaccination is the process of exposing a person to a pathogen on purpose in order to develop immunity. In vaccination, a modified pathogen is usually injected under the skin by a shot. Only part of the pathogen is injected, or a weak or dead pathogen is used. It sounds dangerous, but the shot prepares your body for fighting the pathogen without causing the actual illness. Vaccination triggers an immune response against the injected antigen. The body prepares "memory" cells for use at a later time, in case the antigen is ever encountered again. Essentially, a vaccine imitates an infection, triggering an immune response, without making a person sick.You are aware of B and T cells, special types of white blood cells that help your body to fight off a specific pathogen. They are necessary when the body is fighting off an infection. But what happens to them after the pathogen has been destroyed?
Most B and T cells die after an infection has been brought under control. But some of them survive for many years. They may even survive for a person’s lifetime. These long-lasting B and T cells are called memory cells. They allow the immune system to “remember” the pathogen after the infection is over. If the pathogen invades the body again, the memory cells will start dividing in order to fight the pathogen or disease.
These dividing cells will quickly produce a new army of B or T cells to fight the pathogen. They will begin a faster, stronger attack than the first time the pathogen invaded the body. As a result, the immune system will be able to destroy the pathogen before it can cause an infection. Being able to attack the pathogen in this way is called immunity.
Immunity can also be caused by vaccination. Vaccination is the process of exposing a person to a pathogen on purpose in order to develop immunity. In vaccination, a modified pathogen is usually injected under the skin by a shot. Only part of the pathogen is injected, or a weak or dead pathogen is used. It sounds dangerous, but the shot prepares your body for fighting the pathogen without causing the actual illness. Vaccination triggers an immune response against the injected antigen. The body prepares "memory" cells for use at a later time, in case the antigen is ever encountered again. Essentially, a vaccine imitates an infection, triggering an immune response, without making a person sick.
Which virus was Jenner trying to eliminate?
chickenpox
smallpox
influenza
polio
What is another correct name for a foreign microbe that can invade us, and cause disease is:
antibiotic
antigen
article
pathogen
How do coughing, sneezing, inflammation and fever help the body?
They help rid the body of pathogens.
The let people know you are sick and stay away.
What kind of cells fight specific invaders (pathogens)?
antibiotics
antibigens
T and B cells
red blood cells
In inactive vaccines the viruses are...
living
weak
dead
Why do scientist weaken (attenuate) or kill the pathogen?
so the pathogen does not develop into the full blown disease
so the pathogen doesn't reproduce
so the pathogen can develop into it's full strength
What is the purpose of exposing someone to a weakened or inactive form of a pathogen?
To get them sick and then to trigger the immune response.
To trigger the immune response, and teach the body about the pathogen without getting sick.
To provide a breeding ground for the pathogen
What part of the pathogen actually triggers the immune response?
The antigen
The white blood cells
The antibiotics
The antibodies
What is a DNA vaccine made up of
The DNA of the person protected from the pathogen and will strengthen the immune system.
The specific genes that will instruct the body to make the antigens of a virus and will trigger a stronger immune response.