Developing new drugs 2 OALH

Do Now

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1. Name the plant from which the heart drug digitalis comes.

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2. Name the organism from which the antibiotic penicillin comes.

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3. What process allows bacteria to become resistant to antibiotics?

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4. Name the container shown at right.

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5. Calculate the magnification, when a cell that has a diameter of 10µm is measured at 500mm on a microscope.

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Describe the process of phagocytosis

Key Knowledge

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What 3 things are tested for in pre-clinical and clinical trials?

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What is the medicine tested on in pre-clinical trials?

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What is the medicine tested on in clinical trials?

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What are double-blind trials?

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How is the validity of all scientific data judged?

Recall Quiz

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What is the correct order for drug trials?

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What is a placebo?

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What is a double blind trial?

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What is efficacy of a drug?

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We do: In 2020 the coronavirus killed became a global pandemic. Drug companies have developed a new drug to treat coronavirus. Explain what testing must be done before this new drug can be used to treat people.

Pre-clinical trials of the new drug are carried out on…
These are designed to test the …
Then … are used on … and coronavirus patients at ….
These are used to monitor for …
If it is safe then trials to find …
These are … that randomly allocate a … which does not contain the new drug to patients, so no one knows who …
Finally the data must be…

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You do: In the early 20th century Malaria began to become resistant to the quinine drug that had been used to treat it. Scientists isolated a drug called Artemisinin from a plant. Explain what testing must be done before this new drug can be used to treat people.

Plenary

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1. What plant does the digitalis medicine come from?

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2. Who is the drug tested on during pre-clinical trials?

1

3. What properties of the drug is tested for in pre-clinical and clinical trials?

1

4. Who is the drug tested on in clinical trials?

1

Developing new drugs 2 OALH

1. Name the plant from which the heart drug digitalis comes.

2. Name the organism from which the antibiotic penicillin comes.

3. What process allows bacteria to become resistant to antibiotics?

4. Name the container shown at right.

5. Calculate the magnification, when a cell that has a diameter of 10µm is measured at 500mm on a microscope.

Describe the process of phagocytosis

What 3 things are tested for in pre-clinical and clinical trials?

What is the medicine tested on in pre-clinical trials?

What is the medicine tested on in clinical trials?

What are double-blind trials?

How is the validity of all scientific data judged?

What is the correct order for drug trials?

What is a placebo?

What is a double blind trial?

What is efficacy of a drug?

You do: In the early 20th century Malaria began to become resistant to the quinine drug that had been used to treat it. Scientists isolated a drug called Artemisinin from a plant. Explain what testing must be done before this new drug can be used to treat people.

1. What plant does the digitalis medicine come from?

2. Who is the drug tested on during pre-clinical trials?

3. What properties of the drug is tested for in pre-clinical and clinical trials?

4. Who is the drug tested on in clinical trials?

5. What is a placebo?

1. Name the plant from which the heart drug digitalis comes.

2. Name the organism from which the antibiotic penicillin comes.

3. What process allows bacteria to become resistant to antibiotics?

4. Name the container shown at right.

5. Calculate the magnification, when a cell that has a diameter of 10µm is measured at 500mm on a microscope.

Describe the process of phagocytosis

What 3 things are tested for in pre-clinical and clinical trials?

What is the medicine tested on in pre-clinical trials?

What is the medicine tested on in clinical trials?

What are double-blind trials?

How is the validity of all scientific data judged?

What is the correct order for drug trials?

What is a placebo?

What is a double blind trial?

What is efficacy of a drug?

You do: In the early 20th century Malaria began to become resistant to the quinine drug that had been used to treat it. Scientists isolated a drug called Artemisinin from a plant. Explain what testing must be done before this new drug can be used to treat people.

1. What plant does the digitalis medicine come from?

2. Who is the drug tested on during pre-clinical trials?

3. What properties of the drug is tested for in pre-clinical and clinical trials?

4. Who is the drug tested on in clinical trials?

5. What is a placebo?