Remember the types of mutations
Insertion- One EXTRA DNA base
Deletion- Lost a DNA base
Subsitition- One base is different (different letter)
Silent- Change in the DNA that DOES NOT change the amino acid
Remember the types of mutations
Insertion- One EXTRA DNA base
Deletion- Lost a DNA base
Subsitition- One base is different (different letter)
Silent- Change in the DNA that DOES NOT change the amino acid
Transcribe the DNA sequence:
ACC-CGT-TAT
Transcribe means to turn the DNA into mRNA (A pairs with U)
Translate the mRNA sequence:
UGG-GCA-AUA
Translate means to find the amino acids (use a codon chart)
Transcribe the DNA sequence:
AGC-GAC-CGA-ATT-TC_
Transcribe means to turn the DNA into mRNA (A pairs with U)
Translate the mRNA sequence:
UCG-CUG-GCU-UAA-AG
Translate means to find the amino acids (use a codon chart)
Transcribe the DNA sequence:
GGA-CGC-CGA-AGG
Transcibe means to turn the DNA into mRNA (A pairs with U)
Translate the mRNA sequence
CCU-GCG-GCU-UCC
Translate means to find the amino acids (use a codon chart)
What amino acid does the mutated DNA sequence TAT code for?
Hint:
1. change the TAT into RNA
2. Find the amino acid
What amino acid does the normal DNA sequence TAG code for?
Hint:
1. change the TAG into RNA
2. Find the amino acid
What amino acid does the DNA sequence TCT code for?
What trait does the amino acid sequence code for?
Look at the reference chart. Match the amino acids sequence in #4 to find the trait.
The normal gene A is:
ACC-GGT-TAT and codes for white fur
The mutated gene A is:
ACC-CGT-TAT
There is ONE letter change that is highlighted. What type of mutation is found in gene A?
What trait does the amino acid sequence code for?
Look at the reference chart. Match the amino acids sequence in #6 to find the trait.
The DNA sequence for normal gene B is:
AGA-CGA-CCG-AAT-TTC and codes for short whiskers
The mutated gene B is:
AGC-GAC-CGA-ATT-TC_
The mutated sequence is MISSING one base (letter). What type of mutation is found in gene B?
What trait does the amino acid sequence code for?
Look at the reference chart. Match the amino acids sequence in #10 to find the trait.
The DNA sequence for the normal gene C is:
GGA-CGC-CGA-AGT and codes for blue eyes
The mutated gene C is:
GGA-CGA-CGA-AGG
The mutation DID NOT change the amino acid sequence. What type of mutation has occured in gene C?
Will a person with a mutation of TAT be diabetic?
Will the mutation TCT (instead of the normal TAG) cause a person to be diabetic? Explain your answer.