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DNA HHMI
By Elizabeth Stevens
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Last updated about 2 hours ago
23 questions
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Read Introduction and Part 1 of the handout.
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Question 1
1.
What is the starting flanking sequence:
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title
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Question 20
20.
Type in correct answer to four decimal places Ex: 0.0000
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Question 21
21.
Type in correct answer to four decimal places Ex: 0.0000
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Question 2
2.
What is the ending flanking sequence:
Question 3
3.
Number of repeat units
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Question 4
4.
Write out the STR shown above using genetic shorthand. Example: [GATA]6
Question 5
5.
Is there any way that the daughter in Figure 2 could have been homozygous for the STR shown? Explain your answer.
No, both parents need to have at least one matching STR for daughter to be homozygous.
Yes, parents are both homozygous and heterozygous which is necessary for daughter to be homozygous
Need more information about parent DNA to make a decision.
Question 6
6.
Question 7
7.
Examine the electropherogram in Figure 4. Describe how you determine whether an individual is heterozygous or homozygous for a particular STR.
Two identical numbers are present for the STR which indicates they are heterozygous
Two different numbers are present for the STR which indicates they are heterozygous.
One number is present for the STR which indicates they are homozygous
Two different numbers are present for the STR which indicates they are homozygous.
Question 8
8.
List the STR locus or loci at which this individual is homozygous.
D8S1179
D21S11
D7S820
CSF1PO
Question 9
9.
Which locus has the longest DNA fragments?
D8S1179
D21S11
D7S820
CSF1PO
use handout to complete page
Question 10
10.
# of repeat Alleles 1 AGAT
Question 11
11.
# of repeat Alleles 2 AGAT
Question 12
12.
Homozygous or Heterzygous?
Homo
Hetero
Question 13
13.
# of repeat Alleles 1 TAGA
Question 14
14.
# of repeat Alleles 2 TAGA
Question 15
15.
Homozygous or Heterzygous?
Homo
Hetero
Question 16
16.
# of repeat Alleles 1 GATA
Question 17
17.
# of repeat Alleles 2 GATA
Question 18
18.
Homozygous or Heterzygous?
Homo
Hetero
Question 19
19.
# of repeat Alleles 1 TCTA
Question 22
22.
Type in correct answer to four decimal places Ex: 0.0000
Question 23
23.
Type in correct answer to four decimal places Ex: 0.0000
Using the diagram on the right, identify all of the possible STR allele combinations that the son could have inherited at this particular locus.
6,4
5, 4
4,11
5,11
5,6
6,11
