DNA HHMI

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23 Nsɛmmisa

Read Introduction and Part 1 of the handout.

What is the starting flanking sequence:

What is the ending flanking sequence:

Examine the electropherogram in Figure 4. Describe how you determine whether an individual is heterozygous or homozygous for a particular STR.

Two identical numbers are present for the STR which indicates they are heterozygous

Two different numbers are present for the STR which indicates they are heterozygous.

One number is present for the STR which indicates they are homozygous

Two different numbers are present for the STR which indicates they are homozygous.

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DNA HHMI

DNA HHMI

What is the starting flanking sequence:

What is the ending flanking sequence:

Examine the electropherogram in Figure 4. Describe how you determine whether an individual is heterozygous or homozygous for a particular STR.

Type in correct answer to four decimal places Ex: 0.0000

Type in correct answer to four decimal places Ex: 0.0000

Type in correct answer to four decimal places Ex: 0.0000

Type in correct answer to four decimal places Ex: 0.0000

What is the starting flanking sequence:

What is the ending flanking sequence:

Number of repeat units

Write out the STR shown above using genetic shorthand. Example: [GATA]6

Is there any way that the daughter in Figure 2 could have been homozygous for the STR shown? Explain your answer.

Using the diagram on the right, identify all of the possible STR allele combinations that the son could have inherited at this particular locus.

Examine the electropherogram in Figure 4. Describe how you determine whether an individual is heterozygous or homozygous for a particular STR.

List the STR locus or loci at which this individual is homozygous.

Which locus has the longest DNA fragments?

# of repeat Alleles 1 AGAT

# of repeat Alleles 2 AGAT

Homozygous or Heterzygous?

# of repeat Alleles 1 TAGA

# of repeat Alleles 2 TAGA

Homozygous or Heterzygous?

# of repeat Alleles 1 GATA

# of repeat Alleles 2 GATA

Homozygous or Heterzygous?

# of repeat Alleles 1 TCTA

Type in correct answer to four decimal places Ex: 0.0000

Type in correct answer to four decimal places Ex: 0.0000

Type in correct answer to four decimal places Ex: 0.0000

Type in correct answer to four decimal places Ex: 0.0000

Number of repeat units

Write out the STR shown above using genetic shorthand. Example: [GATA]6

Is there any way that the daughter in Figure 2 could have been homozygous for the STR shown? Explain your answer.

Using the diagram on the right, identify all of the possible STR allele combinations that the son could have inherited at this particular locus.

List the STR locus or loci at which this individual is homozygous.

Which locus has the longest DNA fragments?

# of repeat Alleles 1 AGAT

# of repeat Alleles 2 AGAT

Homozygous or Heterzygous?

# of repeat Alleles 1 TAGA

# of repeat Alleles 2 TAGA

Homozygous or Heterzygous?

# of repeat Alleles 1 GATA

# of repeat Alleles 2 GATA

Homozygous or Heterzygous?

# of repeat Alleles 1 TCTA