Measure of Toxicity Article & Discussion
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Last updated over 3 years ago
15 questions
1
What are the advantages and disadvantages in knowing about the chemicals in our environment and having the ability to measure them in miniscule amounts?
What are the advantages and disadvantages in knowing about the chemicals in our environment and having the ability to measure them in miniscule amounts?
1
Explain what the authors mean when they claim that "zero risk is an impossible goal."
Explain what the authors mean when they claim that "zero risk is an impossible goal."
1
If everything carries some risk, how do we make decisions?
If everything carries some risk, how do we make decisions?
1
Define "toxic" from the context of this article.
Define "toxic" from the context of this article.
1
Explain the concept of LD50.
Explain the concept of LD50.
1
For what types of situations is LD50 relevant?
For what types of situations is LD50 relevant?
1
Briefly explain why LD50 has drawbacks and is considered "outdated" by the authors.
Briefly explain why LD50 has drawbacks and is considered "outdated" by the authors.
1
What is chronic toxicity, and why is that more valuable information for people?
What is chronic toxicity, and why is that more valuable information for people?
1
What are LOAEL and NOAEL and how are these measurements useful?
What are LOAEL and NOAEL and how are these measurements useful?
1
List three chronic toxicity metrics, and how/where they are used.
List three chronic toxicity metrics, and how/where they are used.
1
Identify one substance in each category (color coded based on level of toxicity) and compare the dose that is acutely toxic to the amount on this chart that is of minimal concern. (Don't forget units!). Do any of these surprise you?
Identify one substance in each category (color coded based on level of toxicity) and compare the dose that is acutely toxic to the amount on this chart that is of minimal concern. (Don't forget units!). Do any of these surprise you?
1
Use the example of lead to explain why it is dangerous to oversimplify toxicity of substances.
Use the example of lead to explain why it is dangerous to oversimplify toxicity of substances.
1
Why must we look beyond basic toxicity metrics when assessing risk?
Why must we look beyond basic toxicity metrics when assessing risk?
1
Explain why it may be safe to take a few doses of tylenol at higher levels than the chronic toxicity measurements?
Explain why it may be safe to take a few doses of tylenol at higher levels than the chronic toxicity measurements?
1
"The dose makes the poison." Paracelsus expressed the classic toxicology maxim "All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison." This is often condensed to: "The dose makes the poison" or in Latin, "Sola dosis facit venenum".What statements by the authors in their conclusion support this notion?
"The dose makes the poison." Paracelsus expressed the classic toxicology maxim "All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison." This is often condensed to: "The dose makes the poison" or in Latin, "Sola dosis facit venenum".
What statements by the authors in their conclusion support this notion?