•Distinguish clearly between the terms ‘homeoboxsequence’ and homeodomain sequence’.
•Describe the function of proteins that contain a homeodomain sequence.
•‘Homeoboxsequences are highly conserved’. Explain the significance of this phrase.
•Explain the difference between homeoboxgenes and Hoxgenes
•The Hoxgene Pax6 is necessary for the development of the retina in humans. A mutation in this gene can lead to blindness. Pax6 mutations also cause blindness in mice and fruit flies. Describe how scientists could have tested the idea that Pax6 plays a role in eye development in all three species.
•Consider the statement: ‘All Hoxgenes are homeoboxgenes but not all homeoboxgenes are Hoxgenes.’ Discuss the validity of this statement.