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Homeobox genes

Last updated about 3 years ago

6 questions

1

Question 1

1.

•Distinguish clearly between the terms ‘homeoboxsequence’ and homeodomain sequence’.

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Question 2

2.

•Describe the function of proteins that contain a homeodomain sequence.

Question 3

3.

•‘Homeoboxsequences are highly conserved’. Explain the significance of this phrase.

Question 4

4.

•Explain the difference between homeoboxgenes and Hoxgenes

Question 5

5.

•The Hoxgene Pax6 is necessary for the development of the retina in humans. A mutation in this gene can lead to blindness. Pax6 mutations also cause blindness in mice and fruit flies. Describe how scientists could have tested the idea that Pax6 plays a role in eye development in all three species.

Question 6

6.

•Consider the statement: ‘All Hoxgenes are homeoboxgenes but not all homeoboxgenes are Hoxgenes.’ Discuss the validity of this statement.