Breast Cancer Transfer Task

1

BRCA genes prevent cancer tumors from forming.

True

False

Everyone has two copies of the BRCA2 gene, one copy inherited from each parent. Even if a person inherits a BRCA2 mutation from one parent, they still have the normal copy of the BRCA2 gene from the other parent.

Cancer occurs when a second mutation happens that affects the normal copy of the gene, so the person no longer has a BRCA2 gene that works properly.

1

How many copies of the BRAC2 gene do people have?

1

2

3

4

0

2

State one notice about Figure 1.
YOU MUST USE NUMBERS FROM THE GRAPH

2

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 50?

2

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 70?

2

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female 2nd breast cancer risk by age 70?

2

Figure 2 shows the risk of breast cancer for BRCA2 patients who have different number of full term pregnancies before the age of 30

6

According to the graph, how does the number of full-term pregnancies before the age of 30 affect a BRCA2 patient's breast cancer risk?
Make a claim and provide 2 pieces of evidence from the graph.

1

What age range does the risk of breast cancer increase the most when multiple family members have breast cancer?

Ages 20 to 40

Ages 40 to 60

Ages 60 to 80

3

What is a mutation and how can a mutation lead to cancer?

3

Describe how mutated genes are passed through a family. Consider meiosis in your answer.

1

Why is it useful for patients who test positive for BRCA2 mutations to also see a genetic counselor and not just use the test results to make decisions? (In other words, why is knowing your genetic information not enough?

Even if someone has inherited the mutation, risk of cancer is affected by many variables beyond genes

Genetic information is not enough because test results can be wrong

Family history may be incorrectly reported

Genetic counselors are the only ones who know how to read the test results.

Breast Cancer Transfer Task

BRCA genes prevent cancer tumors from forming.

How many copies of the BRAC2 gene do people have?

State one notice about Figure 1.
YOU MUST USE NUMBERS FROM THE GRAPH

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 50?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 70?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female 2nd breast cancer risk by age 70?

According to the graph, how does the number of full-term pregnancies before the age of 30 affect a BRCA2 patient's breast cancer risk?
Make a claim and provide 2 pieces of evidence from the graph.

What age range does the risk of breast cancer increase the most when multiple family members have breast cancer?

What is a mutation and how can a mutation lead to cancer?

Describe how mutated genes are passed through a family. Consider meiosis in your answer.

Why is it useful for patients who test positive for BRCA2 mutations to also see a genetic counselor and not just use the test results to make decisions? (In other words, why is knowing your genetic information not enough?

BRCA genes prevent cancer tumors from forming.

How many copies of the BRAC2 gene do people have?

State one notice about Figure 1.
YOU MUST USE NUMBERS FROM THE GRAPH

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 50?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 70?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female 2nd breast cancer risk by age 70?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for male breast cancer by age 70?

According to the graph, how does the number of full-term pregnancies before the age of 30 affect a BRCA2 patient's breast cancer risk?
Make a claim and provide 2 pieces of evidence from the graph.

What age range does the risk of breast cancer increase the most when multiple family members have breast cancer?

What is a mutation and how can a mutation lead to cancer?

Describe how mutated genes are passed through a family. Consider meiosis in your answer.

Why is it useful for patients who test positive for BRCA2 mutations to also see a genetic counselor and not just use the test results to make decisions? (In other words, why is knowing your genetic information not enough?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for male breast cancer by age 70?

Breast Cancer Transfer Task

Breast Cancer Transfer Task

BRCA genes prevent cancer tumors from forming.

How many copies of the BRAC2 gene do people have?

State one notice about Figure 1.YOU MUST USE NUMBERS FROM THE GRAPH

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 50?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 70?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female 2nd breast cancer risk by age 70?

According to the graph, how does the number of full-term pregnancies before the age of 30 affect a BRCA2 patient's breast cancer risk?Make a claim and provide 2 pieces of evidence from the graph.

What age range does the risk of breast cancer increase the most when multiple family members have breast cancer?

What is a mutation and how can a mutation lead to cancer?

Describe how mutated genes are passed through a family. Consider meiosis in your answer.

Why is it useful for patients who test positive for BRCA2 mutations to also see a genetic counselor and not just use the test results to make decisions? (In other words, why is knowing your genetic information not enough?

BRCA genes prevent cancer tumors from forming.

How many copies of the BRAC2 gene do people have?

State one notice about Figure 1.YOU MUST USE NUMBERS FROM THE GRAPH

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 50?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 70?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female 2nd breast cancer risk by age 70?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for male breast cancer by age 70?

According to the graph, how does the number of full-term pregnancies before the age of 30 affect a BRCA2 patient's breast cancer risk?Make a claim and provide 2 pieces of evidence from the graph.

What age range does the risk of breast cancer increase the most when multiple family members have breast cancer?

What is a mutation and how can a mutation lead to cancer?

Describe how mutated genes are passed through a family. Consider meiosis in your answer.

Why is it useful for patients who test positive for BRCA2 mutations to also see a genetic counselor and not just use the test results to make decisions? (In other words, why is knowing your genetic information not enough?

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for male breast cancer by age 70?

State one notice about Figure 1.
YOU MUST USE NUMBERS FROM THE GRAPH

According to the graph, how does the number of full-term pregnancies before the age of 30 affect a BRCA2 patient's breast cancer risk?
Make a claim and provide 2 pieces of evidence from the graph.

State one notice about Figure 1.
YOU MUST USE NUMBERS FROM THE GRAPH

According to the graph, how does the number of full-term pregnancies before the age of 30 affect a BRCA2 patient's breast cancer risk?
Make a claim and provide 2 pieces of evidence from the graph.