Breast Cancer Transfer Task

Last updated over 1 year ago
14 questions
1

BRCA genes prevent cancer tumors from forming.

Everyone has two copies of the BRCA2 gene, one copy inherited from each parent. Even if a person inherits a BRCA2 mutation from one parent, they still have the normal copy of the BRCA2 gene from the other parent.

Cancer occurs when a second mutation happens that affects the normal copy of the gene, so the person no longer has a BRCA2 gene that works properly.
1

How many copies of the BRAC2 gene do people have?

0
Cancer occurs when a person has __________ copy of the BRCA2 gene that works properly.
2

State one notice about Figure 1.
YOU MUST USE NUMBERS FROM THE GRAPH

2

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 50?

2

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female breast cancer risk by age 70?

2

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for increased female 2nd breast cancer risk by age 70?

2

By what percentage does the BRCA mutation increase the risk for developing breast cancer and/or ovarian cancer for male breast cancer by age 70?

Figure 2 shows the risk of breast cancer for BRCA2 patients who have different number of full term pregnancies before the age of 30
6

According to the graph, how does the number of full-term pregnancies before the age of 30 affect a BRCA2 patient's breast cancer risk?

Make a claim and provide 2 pieces of evidence from the graph.

1
Beyonce has 3 children and her sister Solange has 1 child. According to the figure, Beyonce's risk for developing breast cancer is __________ than her sister's chance.
1

What age range does the risk of breast cancer increase the most when multiple family members have breast cancer?

3

What is a mutation and how can a mutation lead to cancer?

3

Describe how mutated genes are passed through a family. Consider meiosis in your answer.

1

Why is it useful for patients who test positive for BRCA2 mutations to also see a genetic counselor and not just use the test results to make decisions? (In other words, why is knowing your genetic information not enough?