Below are two partial sequences of DNA bases (shown for only one strand of
DNA) Sequence 1 is from a human and sequence 2 is from a cow. In both
humans and cows, this sequence is part of a set of instructions for controlling a
bodily function. In this case, the sequence contains the gene to make the protein
insulin. Insulin is necessary for the uptake of sugar from the blood. Without
insulin, a person cannot use digest sugars the same way others can, and they
have a disease called diabetes.
-Using the DNA sequence, make a complementary RNA strand from both the human and the cow.
Write the RNA directly below the DNA strand (remember to substitute U's for T's in RNA).
-Use the codon table in your book to determine what amino acids are assembled to make the insulin
protein in both the cow and the human. Write your amino acid chain directly below the RNA
*Note: This is not the real sequence for insulin, which actually contains 51 amino acids. Uniprot provides full sequencing information
on insulin and known variants. http://www.uniprot.org/uniprot/P01308