A wheelchair-bound patient with a relatively painless wound around the medial malleolus has palpable pulses, an ABI of 0.90, pitting edema of the lower extremity, and brownish discoloration around the wound. The wound measures 6 cm (L) x 6 cm (W) x 0.60 cm (D) has red tissue in the base, and large amounts of exudate. Which of the following represents the most appropriate treatment option?