3.04 Mouse Genetics Lab

Last updated about 2 hours ago

36 questions

Note from the author:

Instructions

Required

0.5

Required

0.5

Required

0.5

Required

0.5

Required

0.5

Required

0.5

Required

0.5

Required

1.25

Required

0.5

Required

0.75

Required

0.5

Required

0.5

Required

3.04 Mouse Genetics Lab

Last updated about 2 hours ago

36 questions

Note from the author:

Before you can complete this assignment, you need to click here log in to Gizmos.

Gizmos switched to their new log in system.  Follow the directions in this document to join:

Click here to open the Mouse Genetics Gizmo.
Need help?  Click here to watch the class recording.

Instructions

Before you can complete this assignment, you need to click here log in to Gizmos.

Gizmos switched to their new log in system.  Follow the directions in this document to join:

Click here to open the Mouse Genetics Gizmo.
Need help?  Click here to watch the class recording.

Watch this video to help you review genetics and Punnett Squares:

Required

0.5

Gizmo Warm-up 

Heredity is the passage of genetic information from parents to offspring. The rules of inheritance were discovered in the 19th century by Gregor Mendel. With the Mouse Genetics Gizmo, you will study how one trait, or feature, is inherited.

Drag two black mice into the Parent 1 and Parent 2 boxes. Click Breed to view the five offspring of these parents.

What do the offspring look like? __________

The appearance of each mouse is also called its __________

Required

0.5

Click Clear, and drag two white mice into the parent boxes. Click Breed several times. 

What is the phenotype of the offspring now? __________

Required

0.5

Do you think mouse offspring will always look like their parents? Why or why not?

Required

0.5

Part 1: Patterns of Inheritance

Question: What patterns are shown by offspring traits?

Get the Gizmo ready:
Click Clear.
Drag a black mouse and a white mouse into the parent boxes, but don’t click Breed yet.

Predict: What do you think the offspring of a black mouse and a white mouse will look like?

Required

0.5

Observe: Click Breed several times. What do you see?

Required

0.5

Observe: Drag two offspring into the Holding Cages. These mice are called hybrids because their parents had different traits. Click Clear, and then breed the two hybrids.

What do you see now?

Required

0.5

Experiment: Turn on Show statistics. Click Breed until there are 100 offspring.

How many offspring were black? _______ 
How many offspring were white? _______ 

Required

Explore: Try other combinations of mouse parents.  You can refer to the parents as “pure black,” “pure white,” or “hybrid.”

Which parent combination(s) yield only white offspring? _______ 
Which parent combination(s) yield only black offspring? _______ 
Which parent combination(s) yield a mixture of black and white offspring? _______ 

Required

1.25

Required

Analyze: Dominant alleles are always expressed when present. Recessive alleles are not expressed when the dominant allele is also present. Look at the two alleles for fur color.

Which allele is dominant? __________
What fur color does it produce? __________

Which allele is recessive? __________
What fur color does it produce? __________

Required

0.5

Required

0.75

Required

0.5

Experiment: Click Breed several times, and look at the genotypes of the offspring. Did you find all the predicted genotypes? Explain.

Part 3: Modeling Inheritance

Question: How do scientists predict the genotypes of offspring?

Get the Gizmo ready:
Click Clear.
Drag a black mouse and a white mouse into the parent boxes.
Model: Scientists use a Punnett square to model the different possible offspring genotypes from a parent pair. The parent genotypes are written across the top and side of the square, as shown. The four possible offspring genotypes are then filled in.

Complete the following Punnett square for a homozygous black mouse (FF) and homozygous white mouse (ff).

Required

0.25

Required

0.25

Required

0.25

Required

0.25

Required

What are the genotypes of the offspring? _______ 

What percentage of the offspring will have black fur? _______ 

What percentage of the offspring will have white fur? _______ 

Required

Model: Use the Punnett squares below to model each parent combination. After filling in each Punnett square, predict the percentages of black and white offspring.

Parent 1: Heterozygous black (Ff)
Parent 2: Heterozygous black (Ff)

Required

0.25

Required

0.25

Required

0.25

Required

0.25

Required

Predicted % black offspring: _______ 

Predicted % white offspring: _______ 

Parent 1: Heterozygous black (Ff)
Parent 2: Homozygous white (ff)

Required

0.25

Required

0.25

Required

0.25

Required

0.25

Required

0.5

Predicted % black offspring: _______ 

Predicted % white offspring: _______ 

Required

Experiment: Turn on Show statistics and Show as approximate percentage. For each combination, breed approximately 500 offspring. Record the results below.

(Hint: To obtain an Ff mouse, breed an FF mouse to an ff mouse. Place two Ff offspring into the holding cages, click Clear, and then drag the Ff mice into the parent boxes.)

Parent 1 Genotype          Parent 2 Genotype          % Black Offspring          % White Offspring
             Ff                                          Ff                                  _______                            _______ 
             Ff                                          ff                                  _______                            _______ 

Required

Draw conclusions: How well did the Punnett squares predict the offspring percentages for each parent pair?

Required

Summarize: In your own words, describe what heredity is and how it works in mice.

Part 4: Expanded Punnett Square

Question: How can scientists predict the inheritance of two traits?

Model: Mice have alleles for fur color (F for black, f for white) and eye color (E for black, e for red).  Each parent mouse will contribute one allele for fur color and another for eye color. 

If a parent mouse is Ff Ee, there are four possible allele combinations the parent could pass to its offspring: FE, Fe, fE, and fe. The combinations are written along the top and sides of the expanded Punnett square.

Predict the offspring of two Ff Ee parents.

Required

0.5

Required

0.5

Required

0.5

Required

0.5

3.04 Mouse Genetics Lab

3.04 Mouse Genetics Lab

Click here to open the Mouse Genetics Gizmo.

Need help? Click here to watch the class recording.

Click here to open the Mouse Genetics Gizmo.

Need help? Click here to watch the class recording.

Do you think mouse offspring will always look like their parents? Why or why not?

Observe: Click Breed several times. What do you see?

Observe: Drag two offspring into the Holding Cages. These mice are called hybrids because their parents had different traits. Click Clear, and then breed the two hybrids.

What do you see now?

Experiment: Click Breed several times, and look at the genotypes of the offspring. Did you find all the predicted genotypes? Explain.

Draw conclusions: How well did the Punnett squares predict the offspring percentages for each parent pair?

Summarize: In your own words, describe what heredity is and how it works in mice.

Click here to open the Mouse Genetics Gizmo.

Need help? Click here to watch the class recording.

Click here to open the Mouse Genetics Gizmo.

Need help? Click here to watch the class recording.

Do you think mouse offspring will always look like their parents? Why or why not?

Observe: Click Breed several times. What do you see?

Observe: Drag two offspring into the Holding Cages. These mice are called hybrids because their parents had different traits. Click Clear, and then breed the two hybrids.

What do you see now?

Predict: Place two of the Ff offspring into the Holding Cages. Click Clear, and then place them into the parent boxes.

Which allele(s) could the offspring inherit from each parent? Options may be used more than once.

What are the possible genotypes of the offspring? Select all that apply.

Experiment: Click Breed several times, and look at the genotypes of the offspring. Did you find all the predicted genotypes? Explain.

Experiment: Click Breed several times. Were your predictions correct?

Draw conclusions: How well did the Punnett squares predict the offspring percentages for each parent pair?

Summarize: In your own words, describe what heredity is and how it works in mice.

3.04 Mouse Genetics Lab

3.04 Mouse Genetics Lab

Click here to open the Mouse Genetics Gizmo.

Need help? Click here to watch the class recording.

Click here to open the Mouse Genetics Gizmo.

Need help? Click here to watch the class recording.

Do you think mouse offspring will always look like their parents? Why or why not?

Part 1: Patterns of InheritanceQuestion: What patterns are shown by offspring traits?Get the Gizmo ready:Click Clear.Drag a black mouse and a white mouse into the parent boxes, but don’t click Breed yet.Predict: What do you think the offspring of a black mouse and a white mouse will look like?

Observe: Click Breed several times. What do you see?

Observe: Drag two offspring into the Holding Cages. These mice are called hybrids because their parents had different traits. Click Clear, and then breed the two hybrids.What do you see now?

Experiment: Click Breed several times, and look at the genotypes of the offspring. Did you find all the predicted genotypes? Explain.

Draw conclusions: How well did the Punnett squares predict the offspring percentages for each parent pair?

Summarize: In your own words, describe what heredity is and how it works in mice.

Click here to open the Mouse Genetics Gizmo.

Need help? Click here to watch the class recording.

Click here to open the Mouse Genetics Gizmo.

Need help? Click here to watch the class recording.

Do you think mouse offspring will always look like their parents? Why or why not?

Part 1: Patterns of InheritanceQuestion: What patterns are shown by offspring traits?Get the Gizmo ready:Click Clear.Drag a black mouse and a white mouse into the parent boxes, but don’t click Breed yet.Predict: What do you think the offspring of a black mouse and a white mouse will look like?

Observe: Click Breed several times. What do you see?

Observe: Drag two offspring into the Holding Cages. These mice are called hybrids because their parents had different traits. Click Clear, and then breed the two hybrids.What do you see now?

Predict: Place two of the Ff offspring into the Holding Cages. Click Clear, and then place them into the parent boxes.Which allele(s) could the offspring inherit from each parent? Options may be used more than once.

What are the possible genotypes of the offspring? Select all that apply.

Experiment: Click Breed several times, and look at the genotypes of the offspring. Did you find all the predicted genotypes? Explain.

Experiment: Click Breed several times. Were your predictions correct?

Draw conclusions: How well did the Punnett squares predict the offspring percentages for each parent pair?

Summarize: In your own words, describe what heredity is and how it works in mice.

Observe: Drag two offspring into the Holding Cages. These mice are called hybrids because their parents had different traits. Click Clear, and then breed the two hybrids.

What do you see now?

Observe: Drag two offspring into the Holding Cages. These mice are called hybrids because their parents had different traits. Click Clear, and then breed the two hybrids.

What do you see now?

Predict: Place two of the Ff offspring into the Holding Cages. Click Clear, and then place them into the parent boxes.

Which allele(s) could the offspring inherit from each parent? Options may be used more than once.