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Evo-Devo Despacito: Multi-Modal Connections & Lyrics Interactive (A Capella Science)

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Last updated almost 2 years ago
32 questions
Note from the author:
email me at teneal.metcalf@fwisd.org if you want to mention an error or potential improvement.

This is aligned to A Capella Science's "Evo-Devo" Despacito parody. I have as much rights to their production as they do to the original Despacito.

Content covered:

* Concepts of mitosis and differentiation, their role in development (distinguishes from meiosis/fertilization and binary fission)
* Evolution, natural selection, mutation, development
* Distinguishing between regulatory sequences and coding sequences

* Briefly reinforces monomers & polymers (focusing on nucleic acids and proteins)
* Briefly reinforces mRNA translated to protein/distinguishing from transcription.
* Briefly reinforces differences of prokaryotes, eukaryotes, and viruses

Designed to follow students having already learned about protein synthesis from gene to protein, brief introduction to gene switches as part of genetic medicine, and the basics of evolution. Designed to precede deeper concepts of gene regulation in eukaryotes and Hardy-Weinberg conditions for evolution.
Deep Lyric Read Intro
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Video and Big Picture Questions
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Feedback
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Question 1
1.

You are not expected to get all of these right first go round, though many questions here rely on previous knowledge.

This is a mixture of lyrics prediction and assessment of your understanding of terms, and interpretation practice of a passage, to introduce a new topic. We will watch the video after, then receive a new copy of the lyrics to try again with the key turned on.

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Question 2
2.

See...
One cell divide and decide on a thousand fates
Did you ever figure how they know?

The process of cell division as shown in this lyric is...

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Question 4
4.
Choose an appropriate term for this blank in the lyric. Don't stress about whether it's perfect or not.

Did you ever figure how they know?

We
Are built of modules combined in a planned-out way
Each new _______ must be told where to go
Oh
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Question 6
6.

Match the images with the lyrics from this verse.

Draggable itemarrow_right_altCorresponding Item
arrow_right_alt
Phenotype, the interface for mouse and man
arrow_right_alt
Genotype, the files and the subprograms
arrow_right_alt
What then, are the switches, circuit board, and boot code?
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Question 7
7.
Evo-Devo
Looking at the logic in the ways that we grow

Every __________directed by a signal key code

__________ that can activate, enhance or veto*

Evo-Devo

In this verse, the term veto could be replaced without losing meaning... __________
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Question 8
8.
Signals are controlled by other __________that signal
Calculating in a network labyrinthal
Where the heart and liver and the hands and feet go
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Question 9
9.
Signal mapping tells each region what it ought to be yo
With circuits so deeply built upon
They're __________than the Paleo
The Paleozoic Era baby
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Question 11
11.
The word changes in the above verse refers to _______ in the genome.
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Question 12
12.
See down they cascade like a _______
Like you and I drosophila
The path that makes us optical
Was laid a long long time ago
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Question 14
14.
Set up set up
In a _______ (this is shown in the image; we've seen it before as a concentration __________ from high to low... if you can't come up with it, you'll see it soon!)


On segments embryonic
Split forebrains and asymmetric parts depend upon it
Flipping on genetic switches and logic
From devo to evo
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Question 15
15.
Adult and embryo
Mostly don't evolve in the genes of the (whole) __________
Safer the mutation aimed at regulation
Keep the building blocks and swap their activation

The word that could best replace building blocks in the above verse is... __________
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Question 18
18.
Look at how our spinal segments generate a neat row

Built on a molecular clock
One cycle, one vertebra
One vertebra one vertebra baby

__________ its rate is snakes' developmental cheat code

That and where a lizard's feet grow
They turn off distal aminos

The best synonym for the underlined text is __________.
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Question 19
19.
They in the above verse refers to the _______ .
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Question 20
20.

Evo-Devo

This is how we go from single cells to people
Every generation and in life primeval
Life in variations endless and beautiful
Badaboom!

Draggable itemarrow_right_altCorresponding Item
evolution
arrow_right_alt
from single cells to people
development
arrow_right_alt
primeval
a very long time ago
arrow_right_alt
life in variations endless and beautiful
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Question 22
22.
From devo to evo
Larva to mosquito
Patterns are resolved as the signals proceed yo
Map out a gene with a glow tag
Kill it with a morpholino
Short oligo morpholino baby

From devo to evo
Voyage of the Beagle
Body plans evolve when proteins steer the genome
In this manner life's beauty grows
Aesthetica in vivo
Evo-Devo

If you're asked about morpholinos on the test, they'll give you extra information. What a morpholine usually does is block __________ of mRNA into protein.
Question 23
23.
If you're ever asked about morpholinos (unlikely, though similar concepts might show up), you won't need to know about them; they'll describe the morpholino as done above. You do need to know, though, that...
Other Answer Choices:
RNA
DNA
Question 24
24.

According to the lyrics, what does "Evo-Devo" primarily focus on?

Question 25
25.

What does the song imply about the relationship between evolution and development?

Question 26
26.

Which statement describes a common theme in the song?

Question 27
27.

Which are true messages supported by the lyrics?

Question 28
28.

I feel I learned something from this activity

Question 29
29.

I normally enjoy Biology

Question 30
30.

This assignment would have been better for me if...

Question 31
31.

Anything you would like your teacher to know? Include any suggested refinements.

Question 32
32.

I would like more assignments that are closely linked to music.

Question 3
3.

See
One cell divide and decide on a thousand fates
Did you ever figure how they know?

The concept of 'deciding on a thousand fates' is best described by the process of

Question 5
5.

Now there's a science helping us to understand

How our cells encode this architectural plan
Signalling each other with genetic tools oh

Oh yeah

Wow

This process must happen in...

Question 10
10.

In ___________ pathway
Changes tend to get torpedoed
Where they go calamity goes
As this cyclopic sheep knows...

Question 13
13.

Back before we blew up the Cambrian like a bomb bomb
Now my eye protein can make you see out of your bom bom
And Hedgehog and its relatives like Indian and Sonic

Identify the monomer and function of the underlined term.

Question 16
16.

From devo to evo
Parts have alter egos
Homologs evolved from repeats in the schema
Switch a couple bases in the proper places
You'll be watching flies grow legs out of their faces oh yeah

Select the appropriate polymer and function associated with the underlined term.

Question 17
17.

Signals trigger patterns of complexity so
Switching up the switches of a signalling node
Gives a modular and simple way to evolve

Relate the terms, connecting thoughts from this verse.

Draggable itemarrow_right_altCorresponding Item
coding sequence
arrow_right_alt
butterflies hatch with different genotypes
natural selection
arrow_right_alt
acts on the phenotype; brown butterfly survives and reproduces in brown land
evolution
arrow_right_alt
the frequency of the brown phenotype becomes more common over generations
mutation
arrow_right_alt
controls expression, ex. size, amount, and location of melanated spots on a butterfly's wing
regulatory sequence
arrow_right_alt
is expressed (is transcribed to RNA and translated to protein), ex. melanin to make spots on a butterfly's wing
Question 21
21.
Draggable itemarrow_right_altCorresponding Item
meiosis followed by fertilization
arrow_right_alt
development
mechanisms include mutation and natural selection
arrow_right_alt
evolution
mitosis
arrow_right_alt
sexual reproduction
mitosis followed by differentiation
arrow_right_alt
asexual reproduction, repair