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Laabri

Cell Cycle/Mitosis & Cancer Practice/Review

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Last updated 3 months ago
37 Nsɛmmisa
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Asemmisa {{asɛmmisaAhyɛnsode}}
1.
Mmuae Afoforo a Wobɛpaw:
doubled mom chromosome
doubled dad chromosome
"big" doubled homologous chromosome
mom chromosome
dad chromosome
"small" doubled homologous chromosome
Asemmisa {{asɛmmisaAhyɛnsode}}
2.
Mmuae Afoforo a Wobɛpaw:
G0 - cell doing "job", but not dividing
Cytokinesis - dividing the cell parts and splitting the cell into 2 daughter cells
M phase - mitosis AND cytokinesis
G2 - Gap 2 - cell is preparing for cell division
Mitosis - moving and separating chromosomes
S - DNA synthesis - cell is copying its DNA
G1 - Gap 1 - cell is growing
Asemmisa {{asɛmmisaAhyɛnsode}}
3.

Identify the 4 checkpoints of the cell cycle

Mmuae Afoforo a Wobɛpaw:
S Check Point - is all the DNA duplicated?
G1 Check Point - leave cell cycle to "do job" or commit to divide?
G2 Check Point - is DNA all duplicate correctly and no damage?
M Check Point - are all chromosomes lined up correctly at metaphase?
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4.

What stage of mitosis is this cell in?

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5.

What stage of mitosis is this cell in?

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6.

What other event that is part of cell division (not mitosis) is seen in this image?

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7.

What stage of the cell cycle COULD this cell be in?

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8.

Why do you know this cell is NOT in M phase (mitosis/cytokinesis)?

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9.

What stage of mitosis is this cell in?

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10.

What stage of mitosis is this cell in?

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11.

Put these images in order from first to last

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12.

Match the description of the stage of mitosis with the picture of the stage

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plant cell - metaphase - chromosomes line up at center line.

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plant cell - prophase - begin to see chromosomes coiling up from chromatin

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plant cell - telophase & cytokinesis - chromosomes reach opposite ends of cell & begin to go back to chromatin. Cell wall begins to form between 2 daughter cells

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plant cell - anaphase - chromosomes pulled apart to opposite poles of cell

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Question 13
00:05
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Question 14
00:12
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Question 15
00:16
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Question 16
00:17
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Question 17
00:19
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Question 18
00:20
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19.

What is the final outcome of the M phase?

Question 20
00:06
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Question 21
00:13
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Question 22
00:23
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Question 23
00:32
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Question 24
00:35
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Question 25
00:38
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26.

What is the role of the 4 checkpoints in the cell cycle?

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27.

Match the superpower with the definition

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PROMOTING MUTATIONS

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Superpower of Cancer - cancer cells break free from original tumor and travel through the body to create new tumors in different areas of the body

INVADING TISSUES

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Superpower of Cancer - that allows cells to divide more quickly than normal cells

PROCESSING NUTRIENTS

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Superpower of Cancer - where cell is able to keep the tips of its chromosomes (telomeres) LONG so that cell can continue to divide FOREVER

AVOIDING DETECTION

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Superpower of Cancer - where because cells have acquired some mutations become unstable which then lead to even more mutations (and more superpowers)

EVADING DEATH

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Superpower of Cancer - where cells are able to create and send signals for blood vessels to grow into the tumor so tumor can continue to grow

BECOMING IMMORTAL

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Superpower of Cancer - Cancer cells must avoid detection by the B cells and T cells of the immune system. These cells destroy emerging pre-cancerous cells are normally eliminated by the immune response.

GROWING UNCONTROLLABLY

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SUPERPOWER OF CANCER - Cancers cells do not undergo apoptosis (commit PROGRAMMED CELL DEATH) EVEN when they are damaged.

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28.

What is the job of a "normal" proto-oncogene (not the mutated oncogene)?

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29.

What is the job of a "normal" tumor suppressor gene (not a mutated tumor suppressor gene)?

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30.

Which description(s) of how mutations in genes cause cancer is/are correct?

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31.

Unfortunately most risk factors for cancer are not in an individual's control therefore there is not much any one person can do to lower their risk for cancer

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32.

Explain how cancer cells "get" superpowers?

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33.

Explain what happened in our Cancer Cell Survival Challenge... What happened to MOST or ALL of the cancer cells? WHY?

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34.

Explain what happened in our Cancer Cell Survival Challenge... What DID allow (or would have allowed) one or more cancer cells to survive? WHY?

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35.

If a cancer cell acquired several "superpowers" from mutations that created oncogenes and mutations that "broke" tumor suppressor genes, what could happen to the 4 checkpoints of the cell cycle? Explain.

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36.

Match the cancer treatment with its description (use the links as needed to help)

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Immunotherapy

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A testing method that helps doctors analyze your cancer and choose the most effective treatment plan based on specific features of your cancer cells.

Hormone Therapy

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This type of treatment works by using powerful medicines to kill fast-growing cells in the body, including cancer cells.

Radiation Therapy

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This treatment works by stopping or slowing down cancers that depend on certain hormones to grow, particularly in breast and prostate cancers.

Cancer Surgery

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This treatment uses your body's own natural defenses to help fight cancer cells. It works by boosting your immune system's ability to attack cancer.

Chemotherapy

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This treatment uses special drugs that become activated when exposed to light, destroying cancer cells and other abnormal cells in the body.

Blood Stem Cell Transplant

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This type of therapy uses high-energy waves or particles to destroy or damage cancer cells, making tumors smaller.

Biomarker Testing for Cancer Treatment

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This procedure involves removing blood-forming stem cells, storing them, and returning them to the body after high-dose cancer treatments have been completed.

Targeted Therapy

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Procedure where a surgeon identifies and cuts out/removes a tumor(s) from the patient's body

Photodynamic Therapy

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This treatment specifically blocks cancer growth by targeting particular changes in cancer cells that help them grow and spread.

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37.

Briefly explain how T cell immunotherapy work using the video we watched (Immunotherapy for Cancer: What It Is and Why It’s Used) and using the diagram embedded here.

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13.

What stage is the cell in here?

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14.

What stage of mitosis is seen now?

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15.

What stage of mitosis is seen here?

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16.

What stage of mitosis is seen here?

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17.

What stage of mitosis is seen here?

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18.

What stage of the M phase is happening here that allows the cell to split into 2 daughter cells?

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20.
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21.
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22.
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23.

What stage of mitosis would this be?

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24.

What stage of mitosis would this be?

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25.

What part of M phase is seen here?