🧬 Public Evo-Devo Despacito Song by A Capella Science

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You are not expected to get all of these right first go round, though many questions here rely on previous knowledge.

This is a mixture of lyrics prediction and assessment of your understanding of terms, and interpretation practice of a passage, to introduce a new topic. We will watch the video after, then receive a new copy of the lyrics to try again with the key turned on.

1

See...
One cell divide and decide on a thousand fates
Did you ever figure how they know?

The process of cell division as shown in this lyric is...

1

Choose an appropriate term for this blank in the lyric. Don't stress about whether it's perfect or not.

Did you ever figure how they know?

We
Are built of modules combined in a planned-out way
Each new _______ must be told where to go
Oh

1

1.5

Match the images with the lyrics from this verse.

Draggable item		Corresponding Item
		Phenotype, the interface for mouse and man
		Genotype, the files and the subprograms
		What then, are the switches, circuit board, and boot code?

5.5

6.4

…

1.5

Evo-Devo
Looking at the logic in the ways that we grow

Every __________directed by a signal key code

__________ that can activate, enhance or veto*

Evo-Devo

In this verse, the term veto could be replaced without losing meaning... __________

1

Signals are controlled by other __________that signal
Calculating in a network labyrinthal
Where the heart and liver and the hands and feet go

1

Signal mapping tells each region what it ought to be yo
With circuits so deeply built upon
They're __________than the Paleo
The Paleozoic Era baby

1

The word changes in the above verse refers to _______ in the genome.

1

See down they cascade like a _______ 
Like you and I drosophila
The path that makes us optical
Was laid a long long time ago

1

Set up set up 
In a _______ (this  is shown in the image; we've seen it before as a concentration __________ from high to low... if you can't come up with it, you'll see it soon!)


On segments embryonic
Split forebrains and asymmetric parts depend upon it
Flipping on genetic switches and logic
From devo to evo

1.5

Adult and embryo
Mostly don't evolve in the genes of the (whole) __________
Safer the mutation aimed at regulation
Keep the building blocks and swap their activation

The word that could best replace building blocks in the above verse is... __________

1

2.5

Draggable item		Corresponding Item

1

Look at how our spinal segments generate a neat row

Built on a molecular clock
One cycle, one vertebra
One vertebra one vertebra baby

__________ its rate is snakes' developmental cheat code

That and where a lizard's feet grow
They turn off distal aminos

The best synonym for the underlined text is __________.

1

They in the above verse refers to the _______ .

1

Evo-Devo

This is how we go from single cells to people
Every generation and in life primeval
Life in variations endless and beautiful
Badaboom!

Draggable item		Corresponding Item
		from single cells to people

2

1

From devo to evo
Larva to mosquito
Patterns are resolved as the signals proceed yo
Map out a gene with a glow tag
Kill it with a morpholino
Short oligo morpholino baby

From devo to evo
Voyage of the Beagle
Body plans evolve when proteins steer the genome
In this manner life's beauty grows
Aesthetica in vivo
Evo-Devo

If you're asked about morpholinos on the test, they'll give you extra information. What a morpholine usually does is block __________ of mRNA into protein.

1

If you're ever asked about morpholinos (unlikely, though similar concepts might show up), you won't need to know about them; they'll describe the morpholino as done above. You do need to know, though, that...

According to the lyrics, what does "Evo-Devo" primarily focus on?

1

What does the song imply about the relationship between evolution and development?

1

Which statement describes a common theme in the song?

2

Draggable item		Corresponding Item
coding sequence		butterflies hatch with different genotypes
natural selection		acts on the phenotype; brown butterfly survives and reproduces in brown land
regulatory sequence		the frequency of the brown phenotype becomes more common over generations
evolution		controls expression, ex. size, amount, and location of melanated spots on a butterfly's wing
mutation		is expressed (is transcribed to RNA and translated to protein), ex. melanin to make spots on a butterfly's wing

Draggable item		Corresponding Item
mitosis followed by differentiation		development
mechanisms include mutation and natural selection		evolution
meiosis followed by fertilization		sexual reproduction
mitosis		asexual reproduction, repair

🧬 Public Evo-Devo Despacito Song by A Capella Science

See...
One cell divide and decide on a thousand fates
Did you ever figure how they know?

The process of cell division as shown in this lyric is...

Match the images with the lyrics from this verse.

Evo-Devo

This is how we go from single cells to people
Every generation and in life primeval
Life in variations endless and beautiful
Badaboom!

According to the lyrics, what does "Evo-Devo" primarily focus on?

What does the song imply about the relationship between evolution and development?

Which statement describes a common theme in the song?

See...
One cell divide and decide on a thousand fates
Did you ever figure how they know?

The process of cell division as shown in this lyric is...

Now there's a science helping us to understand

How our cells encode this architectural plan
Signalling each other with genetic tools oh

Oh yeah

Wow

This process must happen in...

Match the images with the lyrics from this verse.

In ___________ pathway
Changes tend to get torpedoed
Where they go calamity goes
As this cyclopic sheep knows...

Signals trigger patterns of complexity so
Switching up the switches of a signalling node
Gives a modular and simple way to evolve

Relate the terms, connecting thoughts from this verse.

Evo-Devo

This is how we go from single cells to people
Every generation and in life primeval
Life in variations endless and beautiful
Badaboom!

Match the term to its definition.

According to the lyrics, what does "Evo-Devo" primarily focus on?

What does the song imply about the relationship between evolution and development?

Which statement describes a common theme in the song?

Which are true messages supported by the lyrics?

See
One cell divide and decide on a thousand fates
Did you ever figure how they know?

The concept of 'deciding on a thousand fates' is best described by the process of

Now there's a science helping us to understand

How our cells encode this architectural plan
Signalling each other with genetic tools oh

Oh yeah

Wow

This process must happen in...

In ___________ pathway
Changes tend to get torpedoed
Where they go calamity goes
As this cyclopic sheep knows...

Back before we blew up the Cambrian like a bomb bomb
Now my eye protein can make you see out of your bom bom
And Hedgehog and its relatives like Indian and Sonic

Identify the monomer and function of the underlined term.

From devo to evo
Parts have alter egos
Homologs evolved from repeats in the schema
Switch a couple bases in the proper places
You'll be watching flies grow legs out of their faces oh yeah

Select the appropriate polymer and function associated with the underlined term.

Match the term to its definition.

Draggable item		Corresponding Item
development		from single cells to people
a very long time ago		primeval
evolution		life in variations endless and beautiful

🧬 Public Evo-Devo Despacito Song by A Capella Science

🧬 Public Evo-Devo Despacito Song by A Capella Science

See...One cell divide and decide on a thousand fatesDid you ever figure how they know?The process of cell division as shown in this lyric is...

Match the images with the lyrics from this verse.

Evo-DevoThis is how we go from single cells to peopleEvery generation and in life primevalLife in variations endless and beautifulBadaboom!

According to the lyrics, what does "Evo-Devo" primarily focus on?

What does the song imply about the relationship between evolution and development?

Which statement describes a common theme in the song?

See...One cell divide and decide on a thousand fatesDid you ever figure how they know?The process of cell division as shown in this lyric is...

Now there's a science helping us to understandHow our cells encode this architectural planSignalling each other with genetic tools ohOh yeahWowThis process must happen in...

Match the images with the lyrics from this verse.

In ___________ pathway Changes tend to get torpedoedWhere they go calamity goesAs this cyclopic sheep knows...

Signals trigger patterns of complexity soSwitching up the switches of a signalling node Gives a modular and simple way to evolveRelate the terms, connecting thoughts from this verse.

Evo-DevoThis is how we go from single cells to peopleEvery generation and in life primevalLife in variations endless and beautifulBadaboom!

Match the term to its definition.

According to the lyrics, what does "Evo-Devo" primarily focus on?

What does the song imply about the relationship between evolution and development?

Which statement describes a common theme in the song?

Which are true messages supported by the lyrics?

SeeOne cell divide and decide on a thousand fatesDid you ever figure how they know?The concept of 'deciding on a thousand fates' is best described by the process of

Now there's a science helping us to understandHow our cells encode this architectural planSignalling each other with genetic tools ohOh yeahWowThis process must happen in...

In ___________ pathway Changes tend to get torpedoedWhere they go calamity goesAs this cyclopic sheep knows...

Back before we blew up the Cambrian like a bomb bombNow my eye protein can make you see out of your bom bomAnd Hedgehog and its relatives like Indian and SonicIdentify the monomer and function of the underlined term.

From devo to evoParts have alter egosHomologs evolved from repeats in the schemaSwitch a couple bases in the proper placesYou'll be watching flies grow legs out of their faces oh yeahSelect the appropriate polymer and function associated with the underlined term.

Match the term to its definition.

See...
One cell divide and decide on a thousand fates
Did you ever figure how they know?

The process of cell division as shown in this lyric is...

Evo-Devo

This is how we go from single cells to people
Every generation and in life primeval
Life in variations endless and beautiful
Badaboom!

See...
One cell divide and decide on a thousand fates
Did you ever figure how they know?

The process of cell division as shown in this lyric is...

Now there's a science helping us to understand

How our cells encode this architectural plan
Signalling each other with genetic tools oh

Oh yeah

Wow

This process must happen in...

In ___________ pathway
Changes tend to get torpedoed
Where they go calamity goes
As this cyclopic sheep knows...

Signals trigger patterns of complexity so
Switching up the switches of a signalling node
Gives a modular and simple way to evolve

Relate the terms, connecting thoughts from this verse.

Evo-Devo

This is how we go from single cells to people
Every generation and in life primeval
Life in variations endless and beautiful
Badaboom!

See
One cell divide and decide on a thousand fates
Did you ever figure how they know?

The concept of 'deciding on a thousand fates' is best described by the process of

Now there's a science helping us to understand

How our cells encode this architectural plan
Signalling each other with genetic tools oh

Oh yeah

Wow

This process must happen in...

In ___________ pathway
Changes tend to get torpedoed
Where they go calamity goes
As this cyclopic sheep knows...

Back before we blew up the Cambrian like a bomb bomb
Now my eye protein can make you see out of your bom bom
And Hedgehog and its relatives like Indian and Sonic

Identify the monomer and function of the underlined term.

From devo to evo
Parts have alter egos
Homologs evolved from repeats in the schema
Switch a couple bases in the proper places
You'll be watching flies grow legs out of their faces oh yeah

Select the appropriate polymer and function associated with the underlined term.