🧬🩸 Sickle Cell and the Central Dogma Intro

Last updated about 1 month ago

43 questions

Note from the author:

meant to accompany HHMI resources and cards. Not finalized; extensive WIP.

Whole Class-Intro with Video

Independent/Partner Investigation

2.5

Creating a Sequence for the Central Dogma

Wayground, Whole-Class

Independent Stage Summaries of Transcription vs Translation

3.5

5.5

Untitled Section 14

1.5

Central Dogma Explainer

BioManBio Game

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Video Lecture

Draggable item		Corresponding Item
		Once upon a time, in a eukaryotic cell far away,
		lived a lovely DNA molecule with nucleotides of gold(1),
		a DNA molecule with two antiparallel strands longer(2) than longcat:
		trapped(3) in a nucleus, its days were quiet,
		and the DNA spent those days replicating its nucleotides(4) with the help of its enzyme friends.
		mRNA(5) was its one-and-only link to the outside.

Draggable item		Corresponding Item
		mRNA can be identified by both its single-stranded nature and because it contains uracil
		the ribosome facilitates binding of tRNA to mRNA
		chargaff's rule determines which tRNA binds where; hydrogen bonds are temporary and easily broken
		each amino acid in the growing polypeptide chain is covalently bonded to the next in primary structure
		eventually, a stop codon signals termination of the translation process, the polypeptide chain is detached, and the ribosome dissociates

Draggable item		Corresponding Item
these are generally proteins, which means they are built from AMINO acids
this suffix means that this molecule is probably an enzyme or other protein
these sad jealous molecules are RNA, riboNUCLEIC acid, messengers; we'll learn more about them later, but not today!
this contains guanine, cytosine, thymine, and adenine

Draggable item		Corresponding Item
		Once upon a time, in a eukaryotic cell far away,
		lived a lovely DNA molecule with nucleotides of gold(1),
		a DNA molecule with two antiparallel strands longer(2) than longcat:
		trapped(3) in a nucleus, its days were quiet,
		and the DNA spent those days replicating its nucleotides(4) with the help of its enzyme friends.
		mRNA(5) was its one-and-only link to the outside.

Match the characters in the comic to their context.