Malaria is caused by
This images shows a single malaria parasite about to enter a human red blood cell
Malaria is caused by
This images shows a single malaria parasite about to enter a human red blood cell
Write 3 take-aways from above video
Malaria is caused by
This images shows a single malaria parasite about to enter a human red blood cell
Match the genotypes with the phenotypes (Hb refers to hemoglobin, A is the normal allele, S is the sickle cell mutation allele
| Stavka koja se može prevući | arrow_right_alt | Odgovarajuća stavka |
|---|---|---|
HbA/HbS | arrow_right_alt | normal hemoglobin/no malarial protection |
HbS/HbS | arrow_right_alt | sickle cell trait (50% of hemoglobin has mutation) - no sickle cells diease & protection against malaria |
HbA/HbA | arrow_right_alt | sickle cell disease |
Put the steps of natural selection in order
Speciation - creation of a new species
Overproduction - too many offspring
Competition
Variation
Differential Reproduction
Differential Survival
| Stavka koja se može prevući | arrow_right_alt | Odgovarajuća stavka |
|---|---|---|
Differential Survival | arrow_right_alt | a population has a mix of people with 3 genotypes; HbA/HbA, HbA/HbS, HbS/HbS |
Variation | arrow_right_alt | Parents have offspring with the 3 possible genotypes in an area that has high malaria infection rates |
Differential Reproduction | arrow_right_alt | People with sickle cell trait (HbA/HbS) have protection against malaria while people who are HbA/HbA have no protection |
Competition | arrow_right_alt | People who have sickle cell trait are more likely to survive in areas with high rates of malaria |
Too many offspring - overproduction | arrow_right_alt | People who have sickle cell trait are more likely to survive in areas with high rates of malaria, therefore are able to reproduce |
Drag the correct percentages for the frequency of the sickle cell trait to the 3 areas on the map (go from left to right on the map)
Why do the dark purple areas of the map have so many more people with sickle cell trait than the area of light purple?
Drag and drop the correct labels onto the map - start with the first box and go across the map from left to right. You can reused the answers!
This images shows a sample of red blood cells of a HbA/HbA person on the left and a HbA/HbS person on the right. The person on the left has malarial parasites in their red blood cells compared to the person on the right. This is because having makes it more difficult for the parasite to live inside the red blood cells. Therefore sickle cell trait a malarial infection
Drag and drop the correct labels to each side of the diagram
Select all the statements that supported by the diagram
2 parents that are both heterozygotes for the sickle cell allele (have sickle cell trait)... what would their genotypes be?
Draw a punnett square and fill out the boxes for the above cross
From the above punnett square, what % of children do not have sickle cell anemia AND have no protection vs. malaria? ______ ______ What % of children do not have sickle cell anemia AND have protection vs. malaria? ______ _____
What % of children have sickle cell anemia? _____ _______ (You can reuse the answers!)
Summarize how CRISPR and gene therapy has "cured" some people of sickle cell disease
On an isolated island in the middle of the Pacific ocean, a group of 50 couples started a new population. Every member of the population was a carrier for sickle cell anemia (sickle cell trait - HbA/HbS). When each couple had children, the cross was HbA/HbS x HbA/HbS. The 50 couples had a total of 224 children - 66 HbA/HbA, 125 HbA/HbS and 33 HbS/HbS. Unfortunately the couple unintentionally brought a breeding population of malaria-carrying mosquitos with them. The mosquitos reproduced and grew their population. Within a few years, the island was full of malaria-carrying mosquitos. Use the dropdowns provided to make predictions as to what would happen to each of the three genotypes as their descendents lived on the island over the next 250 years.
The HbA/HbA genotype (started at 66 of 224) will . The HbA/HbS (sickle cell trait - originally was 125 out of 224) will . The HbS/HbS genotype (sickle cell anemia) will
How would you describe the cause of the change in population of humans on the island over the next 250 years?