Sickle Cell Trait & Malaria - Review of Natural Selection - Stephen J Ryan | Biblioteka

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3

Write 3 take-aways from above video

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1

Malaria is caused by
This images shows a single malaria parasite about to enter a human red blood cell

a mosquito landing on a human

the bite of any type of mosquito

a virus

a single-celled parasite injected into human blood from the bite of a mosquito that carries the parasite

Question 3

01:54

Question 4

04:09

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3

Match the genotypes with the phenotypes (Hb refers to hemoglobin, A is the normal allele, S is the sickle cell mutation allele

Stavka koja se može prevući		Odgovarajuća stavka
HbA/HbS		normal hemoglobin/no malarial protection
HbS/HbS		sickle cell trait (50% of hemoglobin has mutation) - no sickle cells diease & protection against malaria
HbA/HbA		sickle cell disease

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6

Put the steps of natural selection in order

Overproduction - too many offspring
Differential Survival
Variation
Differential Reproduction
Competition
Speciation - creation of a new species

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5

Stavka koja se može prevući		Odgovarajuća stavka
Differential Survival		a population has a mix of people with 3 genotypes; HbA/HbA, HbA/HbS, HbS/HbS
Variation		Parents have offspring with the 3 possible genotypes in an area that has high malaria infection rates
Differential Reproduction		People with sickle cell trait (HbA/HbS) have protection against malaria while people who are HbA/HbA have no protection
Competition		People who have sickle cell trait are more likely to survive in areas with high rates of malaria
Too many offspring - overproduction		People who have sickle cell trait are more likely to survive in areas with high rates of malaria, therefore are able to reproduce

Obavezno

3

Drag the correct percentages for the frequency of the sickle cell trait to the 3 areas on the map (go from left to right on the map)

Drugi mogući odgovor:

> 20% of the population (20 people out of 100 total people have sickle cell trait

< 1% of the population (less than 1 person out of 100 people have sickle cell trait)

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1

Why do the dark purple areas of the map have so many more people with sickle cell trait than the area of light purple?

These are the lowlands of the country with more standing water/humidity for mosquitos that carry malaria to reproduce in

It is a random coincidence

These are the highlands of the country with more standing water/humidity for mosquitos that carry malaria to reproduce in

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1

Drag and drop the correct labels onto the map - start with the first box and go across the map from left to right. You can reused the answers!

Drugi mogući odgovor:

area where sickle cell trait would be strongly selected for

area where sickle cell trait would be selected against by natural selection

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3

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2

Drag and drop the correct labels to each side of the diagram

Drugi mogući odgovor:

Area with high malaria

Area with low malaria

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2

Select all the statements that supported by the diagram

Sickle cell allele frequency is correlated (goes up and down together) with levels of malaria across the world

In areas where there is low malaria infections, those populations have high levels of sickle cell trait

people who are born with sickle cell trait are more susceptible to malarial infections

an area with a sickle cell allele frequency of .18 (18% or 18 people out of 100) would like have a low rate of malarial infections

areas with high frequencies of sickle cell trait will also have high levels of sickle cell anemia

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1

2 parents that are both heterozygotes for the sickle cell allele (have sickle cell trait)... what would their genotypes be?

HbA/HbS x HbS/HbS

HbA/HbA x HbA/HbS

HbA/HbS x HbA/HbS

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1

Draw a punnett square and fill out the boxes for the above cross

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1

Drugi mogući odgovor:

50%

25%

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5

Summarize how CRISPR and gene therapy has "cured" some people of sickle cell disease

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1

How would you describe the cause of the change in population of humans on the island over the next 250 years?

random chance

natural selection

Sickle Cell Trait & Malaria - Review of Natural Selection

Sickle Cell Trait & Malaria - Review of Natural Selection

Write 3 take-aways from above video

Malaria is caused by
This images shows a single malaria parasite about to enter a human red blood cell

Describe the effect malaria has had on the human species over our history?

Describe how the parasite enters the body and spreads to cause malarial disease

Match the genotypes with the phenotypes (Hb refers to hemoglobin, A is the normal allele, S is the sickle cell mutation allele

Put the steps of natural selection in order

Why do the dark purple areas of the map have so many more people with sickle cell trait than the area of light purple?

Select all the statements that supported by the diagram

2 parents that are both heterozygotes for the sickle cell allele (have sickle cell trait)... what would their genotypes be?

Draw a punnett square and fill out the boxes for the above cross

Summarize how CRISPR and gene therapy has "cured" some people of sickle cell disease

How would you describe the cause of the change in population of humans on the island over the next 250 years?

Write 3 take-aways from above video

Malaria is caused by
This images shows a single malaria parasite about to enter a human red blood cell

Describe the effect malaria has had on the human species over our history?

Describe how the parasite enters the body and spreads to cause malarial disease

Match the genotypes with the phenotypes (Hb refers to hemoglobin, A is the normal allele, S is the sickle cell mutation allele

Put the steps of natural selection in order

Why do the dark purple areas of the map have so many more people with sickle cell trait than the area of light purple?

Select all the statements that supported by the diagram

2 parents that are both heterozygotes for the sickle cell allele (have sickle cell trait)... what would their genotypes be?

Draw a punnett square and fill out the boxes for the above cross

Summarize how CRISPR and gene therapy has "cured" some people of sickle cell disease

How would you describe the cause of the change in population of humans on the island over the next 250 years?

Sickle Cell Trait & Malaria - Review of Natural Selection

Sickle Cell Trait & Malaria - Review of Natural Selection

Write 3 take-aways from above video

Malaria is caused byThis images shows a single malaria parasite about to enter a human red blood cell

Match the genotypes with the phenotypes (Hb refers to hemoglobin, A is the normal allele, S is the sickle cell mutation allele

Put the steps of natural selection in order

Why do the dark purple areas of the map have so many more people with sickle cell trait than the area of light purple?

Select all the statements that supported by the diagram

2 parents that are both heterozygotes for the sickle cell allele (have sickle cell trait)... what would their genotypes be?

Draw a punnett square and fill out the boxes for the above cross

Summarize how CRISPR and gene therapy has "cured" some people of sickle cell disease

How would you describe the cause of the change in population of humans on the island over the next 250 years?

Write 3 take-aways from above video

Malaria is caused byThis images shows a single malaria parasite about to enter a human red blood cell

Match the genotypes with the phenotypes (Hb refers to hemoglobin, A is the normal allele, S is the sickle cell mutation allele

Put the steps of natural selection in order

Why do the dark purple areas of the map have so many more people with sickle cell trait than the area of light purple?

Select all the statements that supported by the diagram

2 parents that are both heterozygotes for the sickle cell allele (have sickle cell trait)... what would their genotypes be?

Draw a punnett square and fill out the boxes for the above cross

Summarize how CRISPR and gene therapy has "cured" some people of sickle cell disease

How would you describe the cause of the change in population of humans on the island over the next 250 years?

Malaria is caused by
This images shows a single malaria parasite about to enter a human red blood cell

Malaria is caused by
This images shows a single malaria parasite about to enter a human red blood cell