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Gr8 Science Unit 5 End of Unit Assessment

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22 questions
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1. Ensure all tabs on your Chromebook are closed before beginning your assessment.
2. You will be given 70 minutes to complete your Unit 5 End of Unit Assessment.
3. You must work independently, and you may not speak with each other while the test is being administered.
4. You are to answer ALL questions in all parts of this examination. Be sure ALL your answers are in this examination marked on the computer.
1. Ensure all tabs on your Chromebook are closed before beginning your assessment.
2. You will be given 70 minutes to complete your Unit 5 End of Unit Assessment.
3. You must work independently, and you may not speak with each other while the test is being administered.
4. You are to answer ALL questions in all parts of this examination. Be sure ALL your answers are in this examination marked on the computer.
Base your answers to questions 1 and 2 on the passage below and on your knowledge of biology.
1
1
Question 3
3.

Question 4
4.

Question 5
5.

Question 6
6.

Question 7
7.

Question 8
8.

Some viruses can enter cells by first attaching to the cell membrane. The flu virus targets and attaches to the cells of the nose and mouth. The hepatitis virus targets only specific cells of the liver.

Most people who get vaccinated develop immunity to the disease. Explain why the contents of the vaccine usually do not cause people to get sick.

Anticancer Vaccines Become Personalized

Researchers are investigating a personalized approach to create an anticancer vaccine from a patient’s own tumor cells. Some white blood cells are removed and grown with proteins unique to these cancer cells. The patient’s white blood cells are changed by incorporating these proteins from the cancer cells. These altered blood cells can now work as a cancer vaccine. The cancer vaccine is transferred into the patient, and it stimulates the immune system to attack the cancer cells.
1
Question 10
10.

Question 11
11.

Base your answers to questions 12 through 14 on the information below and on your knowledge of biology
1
1
1
Question 15
15.

Question 16
16.

Question 17
17.

Question 18
18.

Question 19
19.

Question 20
20.

Question 21
21.

Question 22
22.

Complete question 22-23 on a separate piece of paper*

Question 1
1.

Identify one specific difference, other than it is a two-step vaccination, between Nabel’s vaccination and a traditional flu vaccine.

Question 2
2.

Explain how injecting dead or weakened viruses into a person can help to fight against future infections from that virus.

The graph below provides information about the number of mitochondria in various types of cells.



Which type of cells most likely require the greatest input of oxygen?
White blood cells
Skin cells
Fat cells
Liver cells
When the human body is responding to stress, the hormone adrenaline is released. A short time later, the body returns to normal. This is an example of how a human:
reacts to an antibody
develops genetic variation in body cells
maintains cellular organization
maintains dynamic equilibrium
A student received a flu shot in the fall. During the flu season, the student caught a cold. The most likely reason the vaccine he received did not prevent the cold was that:
his illness was not caused by a pathogen
he did not get the vaccine at the right time of year
his body produced antibiotics in response to the vaccine
the vaccine he received contained only flu virus antigens

In the diagram, arrows labeled X and Y represent the use of:
clones
receptors
genes
enzymes
The human body fights an infection when a pathogen is detected. As a result, the pathogen stimulates the production of:
bacteria
antibodies
vaccines
antibiotics
The diagram below represents a process that involves an anticancer vaccine.

Question 9
9.

Describe the specific process that is carried out at Step C:

Which substances usually stimulates an immune response?
antibodies
antigens
carbon dioxide molecules
biological catalysts
Antibodies produced against one pathogen infecting the human body may not work against a different pathogen because antibodies are:
only produced once in the body so they can’t work on any other infection
unable to produce effective antibiotics against the infection
made of DNA the second pathogen doesn’t contain
specific for the shape of the proteins present on a particular pathogen
Question 12
12.

State whether the new drug used without the chemotherapy drug would enable the immune system to successfully attack the cancer cells. Support your answer.

Question 13
13.

Explain the role of white blood cells in the process of killing cancer cells:

Question 14
14.

Explain why this new cancer treatment would most likely be less effective if the cancer patient also had AIDS.

After a kidney transplant, special medications are taken. Otherwise, the patient’s immune system might react to the transplanted kidney by:
producing specialized proteins that would attack the kidney
signaling the body to synthesize new DNA molecules
stimulating the circulatory system to attack red blood cells
stimulating the kidney to produce reproductive hormones
Some viruses attack cells by attaching to their outer covering, entering, and taking over their genetic “machinery.” Viruses are able to invade cells after first attaching to their:
nuclear membrane
cell membrane
genetic machinery
viral proteins
Which characteristic is common to most types of cancer?
production of low levels of ATP
inadequate levels of antigens
rapid and uncontrolled cell division
destruction of red blood cells
Experiments in mice show that a guardian gene that protects against type 1 diabetes can be altered by exposure to antibiotics during development. The exposure alters the gut bacteria, leading to a loss of the guardian gene’s protection. The loss of this protection most directly interferes with:
homeostasis
excretion
reproduction
respiration
In order to prepare for a future outbreak of Ebola, a harmful virus, two vaccines were tested. In order for either of these vaccines to be effective, they must:
cause the immune system to produce special proteins that will recognize and destroy the virus
be able to destroy the DNA code that produces white blood cells that can carry the virus
stimulate the human body to produce antigens that can attach to and destroy the Ebola virus
produce bacterial cells that can attack the Ebola virus
Many adults lack the ability to digest the milk sugar, lactose. Often, this is due to the insuffi cient production of the enzyme lactase, which breaks down lactose. This is not due to an allergy to milk. Milk allergies are different because they:
are often not harmful to the person
result in a build-up of the substance in the body
are the result of the digestive system attacking the substance
result from an overreaction of the immune system to a harmless substance
Jean-Baptiste Lamarck was a French naturalist who proposed the idea that modern-day organisms developed new characteristics through a process known as the inheritance of acquired traits. As more evidence became available, this theory was eventually replaced by Charles Darwin’s theory of evolution. This modification of scientific knowledge illustrates that:
scientists do not communicate with each other and often make mistakes
all scientific explanations are tentative and subject to change or improvement
scientists often ignore evidence that does not help prove their theory
hypotheses seldom change even when new discoveries are made