Do First: Competetive Vs. Non-Competetive Inhibition

Last updated 11 months ago
3 questions
1

Certain chemicals _______ with enzymes & make them not work as well.

This is called enzyme inhibition & the chemicals that cause it are called _______. To understand how enzyme inhibitors work you must know a bit about how enzymes normally function.

Usually substrates fit into the _______ of an enzyme where the reaction is helped along. One way that an inhibitor can function is by _______ the active site. This is called _______ inhibition because the competitive inhibitor competes with the substrate for the active site. If the inhibitor beats the _______ to the active site the substrate can't get in & the reaction can't happen.
1

Another type of inhibition is _______ inhibition. It is also known as allosteric inhibition. A non-competitive inhibitor does not _______ for the active _______.

Instead it attaches to a different place on the enzyme known as an _______ site. This changes the _______ of the enzyme so that it can no longer bind to the substrate.
1
A bit of review:

A) What is the primary function of enzymes in biological systems? __________

B) What is the basic structure of an enzyme? __________

C) What is the induced fit? __________

D) How do enzymes affect chemical reactions? __________

E) __________change the shape of the active site preventing the substrate from binding.