2006/L18- Introduction to cell cycle

Last updated 5 months ago
15 questions
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1

Which of the following is the most critical function of the G1 phase in the eukaryotic cell cycle

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During which checkpoint is the activation of APC/C most critical?

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What would be the most likely outcome for a cell that cannot repair severe DNA damage and cannot proceed through the G2/M checkpoint?

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Which of the following events occurs only once per cell cycle and must be strictly regulated?

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In budding yeast, which of the following experimental tools is primarily used to study essential cell cycle genes?

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A fission yeast mutant with defective Rad9 protein fails to pause in G2 after DNA damage. What does this indicate about Rad9’s role?

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What is the primary purpose of the spindle assembly checkpoint (SAC)?

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Which pair of model organisms has been most influential in identifying Cdk1/Cdc2 activity?

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If a mutation in a cell prevents degradation of Cyclin B, what phase transition is most likely to be affected?

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Which best explains why synchronous cells are preferred for biochemical studies of the cell cycle?

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A researcher adds progesterone to Xenopus oocytes. What immediate response should be expected?

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Which is the best explanation for why uncontrolled progression through the cell cycle is dangerous?

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In which cell cycle phase are centrosomes duplicated?

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What is a defining structural feature of a chromosome that enables attachment of spindle fibers during mitosis?

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Which checkpoint ensures that environmental signals and DNA integrity are appropriate before a cell commits to a new cycle?