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Protein Folding Toober Activity Guide

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Last updated 6 months ago
18 questions
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This formative checks understanding of key ideas from the introduction to the protein folding activity (structure → function, amino acid properties) and then guides students through reasoning questions during and after the hands-on 15-tack + mini-toober folding activity. Use these questions for a warm-up, group guide, or exit ticket.
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Which interaction helps stabilize a folded protein structure?
Disulfide bridges exclusively
Van der Waals forces only
Hydrogen bonds between amino acids
Ionic bonds in the backbone
What happens when a protein denatures?
It gains new functions
It loses its functional shape
It becomes larger
It changes color
Why do certain amino acids attract or repel each other?
Due to their size
Because of their chemical properties
Based on their shape
Because of their color
What determines a protein's function in the cell?
The type of cell it is in
Its amino acid sequence
The size of the protein
Its unique three-dimensional structure