{{asɛmtiNe Ɔkyerɛwfo}} | Nhomakorabea | Nneɛma a ɛma wotumi yɛ ade

Background:

null Figure 1: Image of a Mexican Hairless dog the Xoloitzcuintli (Xolo)

The Mexican Hairless Dog or Xoloitzcuintli (Xolo) is an ancient breed of dog that traces its ancestry to the time of the Aztecs. It is the national breed of Mexico and a Xolo named Dante was recently featured in the Disney movie Coco. Not all Xolos are born hairless. Xolos that are born with hair are called coated Xolos.

null Figure 2: Photograph of Hairless and Coated Xolo.

null Figure 3: Skull and teeth structures in Hairless and Coated Xolos

null Figure 4: FOXI3 gene locations in Hairless and Coated Xolos

Additional Data:

Scientists identified the FOXI3 mutation in both the Hairless Xolo and the Hairless Chinese Crested Dog shown to the right. They also identified a similar FOXI3 gene in mice. Experiments revealed that the gene codes for a protein important in whisker, hair and teeth development.

null Figure 5: Image of a Hairless Chinese Crested Dog

1

Use the previous text and images about the Xolo dog to write 2 sentences, one comparing the similarities of figure 2, and one the differences of figure 2.

1

Use the previous text and images about the Xolo dog to write 2 sentences, one comparing the similarities of figure 3, and one the differences of figure 3.

1

Use the previous text and images about the Xolo dog to write 2 sentences, one comparing the similarities of figure 4, and one the differences of figure 4.

6

Breeding Xolos:

Breeding two Hairless Xolos (as shown in the Punnett Square to the left) will create puppies with a ratio of 2 Hairless :1 Coated. However, puppies that receive both copies of the hairless gene will not survive.

(HH) (25%) - Homozygous Hairless- Death, lethal genes
(Hh) (50%) - Heterozygous Hairless Xolo
(hh) (25%) - Homozygous Coated Xolo

In the space below, explain why some Xolo dogs are hairless and others have fur. Your explanation must include and highlight the following words: gene, chromosome, protein, trait, organism, and mutation. Use the information from the text and images to support your answer.

3

Is the mutant FOXI3 gene in Xolos beneficial, neutral or harmful? Explain your thinking.

3

Order the sequence of a mutation chain reaction

Protein
DNA
Cell Function
Gene
Mutation
mRNA

1

What is the genetic disease the Fugate family had?

Methemoglobinemia

Methemoproteinemia

Chromoglobinemia

Crystalglobinemia

1

A mutation can happen that has no change to a protein

Nokorɛ

Ɛnyɛ ampa

Ɛhia

1

Protein Synthesis is

The way traits are passed from parents to offspring

The process by which cells copy DNA during cell division

The process by which cells make proteins using instructions from DNA

The movement of chromosomes during mitosis

Ɛhia

1

Meiosis is a type of cell division that results in two daughter cells each with half the number of chromosomes of the parent cell

True

False

Ɛhia

1

What molecule carries genetic information from the DNA to the Ribosome?

Protein

tRNA

Lysosome

mRNA

Unit 2 Seq 2 Assessment

Unit 2 Seq 2 Assessment

Use the previous text and images about the Xolo dog to write 2 sentences, one comparing the similarities of figure 2, and one the differences of figure 2.

Use the previous text and images about the Xolo dog to write 2 sentences, one comparing the similarities of figure 3, and one the differences of figure 3.

Use the previous text and images about the Xolo dog to write 2 sentences, one comparing the similarities of figure 4, and one the differences of figure 4.

Is the mutant FOXI3 gene in Xolos beneficial, neutral or harmful? Explain your thinking.

Order the sequence of a mutation chain reaction

What is the genetic disease the Fugate family had?

A mutation can happen that has no change to a protein

Protein Synthesis is

Meiosis is a type of cell division that results in two daughter cells each with half the number of chromosomes of the parent cell

What molecule carries genetic information from the DNA to the Ribosome?

Use the previous text and images about the Xolo dog to write 2 sentences, one comparing the similarities of figure 2, and one the differences of figure 2.

Use the previous text and images about the Xolo dog to write 2 sentences, one comparing the similarities of figure 3, and one the differences of figure 3.

Use the previous text and images about the Xolo dog to write 2 sentences, one comparing the similarities of figure 4, and one the differences of figure 4.

Is the mutant FOXI3 gene in Xolos beneficial, neutral or harmful? Explain your thinking.

Order the sequence of a mutation chain reaction

What is the genetic disease the Fugate family had?

A mutation can happen that has no change to a protein

Protein Synthesis is

Meiosis is a type of cell division that results in two daughter cells each with half the number of chromosomes of the parent cell

What molecule carries genetic information from the DNA to the Ribosome?