Blood can be separated in a centrifuge into plasma and formed elements.
Based upon the model, what are formed elements?
Approximately what percentage of a typical blood sample is composed of white blood cells and platelets?
Based upon the model, come up with a description of the shape of an erythrocyte (red blood cell).
What flying-disc toy do erythrocytes resemble?
If you had one of those toys and it was 7.5-inches in diameter and you wanted to get it into a 6-inch diameter pipe, how would you fit it?
Some capillaries are less then 6 micrometers in diameter. Given the answer to the previous questions, explain why erythrocytes might be shaped the way they are.
EPO = erythropoietin
Based on this model, where do erythrocytes come from?
What do erythrocytes do?
What stimulates the production of more erythrocytes?
a.) What stimulates the release of more erythropoietin?
b.) What inhibits the release of erythropoietin?
What is the relationship between erythrocytes and the oxygen-carrying capacity of the blood implied in this model?
a.) How long do erythrocytes live?
b.) Is there a nucleus inside the erythrocytes in model 2?
c.) Can a cell make mRNA without DNA?
d.) Can a cell make proteins without mRNA?
Consider your answers to 13. Why do erythrocytes have a finite lifespan?
If you were to weigh an erythrocyte, about 1/3 of the weight would be the protein hemoglobin.
a.) What is the function of an erythrocyte?
b.) Since erythrocytes have 100x more hemoglobin than any other protein and knowing the function of an erythrocyte, what is the function of hemoglobin?
Create a flowchart that describes the process by which hemoglobin is recycled.
Note: bilirubin and biliverdin are the only components that are removed as waste (bile pigments are part of feces), so don't forget to account for the globin and the iron.
Vegans often suffer from a form of anemia (lowered oxygen carrying capacity of the blood). What nutrients are they likely lacking from their diet?
Construct a flowchart to describe the lifecycle of an erythrocyte starting from the body's need to make it to its eventual destruction and recycling of its contents.
Lance Armstrong was caught cheating in a Tour de France (bicycling) race because his blood showed abnormally high levels of erythropoietin. What advantage would an endurance athlete like a bicyclist have by taking extra erythropoietin?