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Bibliotek

Cell Cycle Disruptions + Immortal Cells

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Sidst opdateret 20 days ago
20 Spørgsmål
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Spørgsmål 1
1.

Each step of the cell cycle is important to make sure healthy daughter cells are formed.

Which of the following best describes what would happen if the cell does NOT successfully complete G1?

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2.

Each step of the cell cycle is important to make sure healthy daughter cells are formed.

Which of the following best describes what would happen if the cell does NOT successfully complete S phase?

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3.

Each step of the cell cycle is important to make sure healthy daughter cells are formed.

During mitosis, DNA moves within the cell. Which of the following could result if the spindle fibers do not form?

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4.

Each step of the cell cycle is important to make sure healthy daughter cells are formed.

During mitosis, DNA moves within the cell. Which of the following could result if the chromosomes are not separated evenly during anaphase?

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5.

Which of the following best describes cancer?

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6.

When cells lose their ability to regulate the cell cycle, they can divide at an accelerated rate and form a mass of cells. This mass of cells is referred to as...

Spørgsmål 7
7.

What is the role of a tumor suppressor gene?

(Select 3)

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8.

During the G2 checkpoint, if there is an unfixable error, the cell will go through apoptosis, this is when . . .

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9.

If we have genes that protect us against cancer, why does cancer still exist?

(Select 3)

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10.

What are some things that cause cancer?

(select 4)

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11.

What are carcinogens?

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12.

What are some examples of carcinogens?

(select 3)

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13.

It is possible to be born with genetics that enhance the chances of developing cancer.

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14.

Actress Angelina Jolie's mother was diagnosed with breast cancer caused by an excess amount of estrogen (a hormone that contributes to building breast tissue).

Angelina Jolie elected to have a double mastectomy, a surgery to remove the breast tissue. She made this decision since she was worried for her own likelihood of developing breast cancer.

Why was Angelina so worried that she would have breast cancer?

The Immortal Cells of Henrietta Lacks

Henrietta Lacks sadly passed away from cervical cancer at the age of 31. However, her cells continue to be grown and used in laboratories to this day. We call her cells HeLa Cells, and they are the first "immortal" cell line in the world because they continue to reproduce where normal cells would have already died.

When she went to Johns Hopkins Hospital for treatment in 1951, she was originally diagnosed with an epidermoid carcinoma in her cervix (this is the scientific way of saying she had a tumor growing in her reproductive tract). Without her knowledge or permission, a sample of her cells were taken for testing and grown inside one of the laboratories in the hospital.

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15.

Why do we consider HeLa cells to be "immortal"?

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Spørgsmål 16
16.

What was Henrietta Lacks diagnosed with?

Why are HeLa Cells Important?

Up until 1951, scientists were unable to keep cells alive in the laboratory. HeLa cells were special because they could be kept alive and grown in the lab over and over again.

These cells were sent across the globe and grown in labs all over the world.

Due to the immortal nature and durability of HeLa cells, they have been used to develop a vaccine for Polio, and have also been used to study diseases such as measles, mumps, HIV, leukemia, and ebola.

Scientists learned that human cells have 46 chromosomes after studying HeLa cells- even though HeLa cells themselves have 80 mutated chromosomes.

These cells were also the first cells to ever be cloned, have traveled to outer space, and were even used in research for a COVID-19 vaccine.

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17.

What makes HeLa cells important?

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HeLa Cell Controversy?

While HeLa cells are an important part of medical research and have been used to help millions of people across the world, many people question the ethics behind using these cells.

Remember, Henrietta Lacks never gave permission or consent to have her cells taken and grown in the laboratory. At the time, the doctor who took her cells also did not know that her cells would be immortal.

Her family was not told that her cells were taken and grown in labs, and they did not find out that her cells had already been sent across the world until over 20 years later.

Her family still has not received any compensation (money) from any research facilities who use HeLa cells in their labs and who have profited from discoveries using her cells.

Henrietta Lacks herself lived in poverty, and her family continues to live in poverty. When interviewed, her daughter said "..if our mother cells done so much for medicine, how come her family can’t afford to see no doctors?"

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20.

Do you think scientists should be able to use HeLa cells for medical research, even though Henrietta Lacks never gave permission for her cells to be used that way?

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18.

What have HeLa cells been used for?

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19.

How many chromosomes are in a normal human cell?