Figure 9.8 A receptor tyrosine kinase is an enzyme-linked receptor with a single transmembrane region, and
extracellular and intracellular domains. Binding of a signaling molecule to the extracellular domain causes the
receptor to dimerize. Tyrosine residues on the intracellular domain are then autophosphorylated, triggering a
downstream cellular response. The signal is terminated by a phosphatase that removes the phosphates from the
phosphotyrosine residues.