Twa kɔ nsɛm atitiriw so
Log in
Sign up for FREE
arrow_back
Laabri

Pedigree Chart Analysis (GF)

star
star
star
star
star
Last updated about 7 years ago
10 Nsɛmmisa

Queen Victoria's Family

1
1
1
1
1
1
1
1
1
1
Asemmisa {{asɛmmisaAhyɛnsode}}
1.

Victoria's youngest child, Beatrice, had one daughter, one normal son, and two sons with hemophilia. Beatrice's daughter, Eugenie, married King Alfonso XIII of Spain. They had six children, one of whom was the father of Juan Carlos, King of Spain. What is Juan Carlos's phenotype?

Asemmisa {{asɛmmisaAhyɛnsode}}
2.

Victoria's daughter, Alice, had a daughter, Alix, who carried the defective allele into the royal Russian family when she married Tsar Nicholas II. They had four daughters and one son, Alexis. Alexis had hemophilia. The entire family was murdered during the Russian Revolution. What is the probability that one of Alexis's sisters was a carrier?

Asemmisa {{asɛmmisaAhyɛnsode}}
3.

What is the probability that all four of Alexis's sisters are carriers?

Finding probability for sequential events - multiply the probability for one sister by the probability for the next sister and so forth
Asemmisa {{asɛmmisaAhyɛnsode}}
4.

If Alexis had lived and married a normal woman and they had a daughter, what is the probability that his daughter would have hemophilia?

Remember that the hemophilia gene is on the "X" chromosome. Alexis would contribute his "X" chromosome to his daughters. His wife, normal and not a carrier, would also contribute an "X" chromosome to their daughter. With two "X" chromosomes, a deleterious allele can be masked by an allele that isn't deleterious.
Asemmisa {{asɛmmisaAhyɛnsode}}
5.

If Alexis had lived and married a normal woman and they had a son, what is the probability that a son would have hemophilia?

Remember that the hemophilia gene is on the X chromosome. Alexis would contribute a "Y" chromosome for his sons. Sons "X" chromosome would come from their mother who is normal (not a carrier).
Asemmisa {{asɛmmisaAhyɛnsode}}
6.

Is it possible for a female to have hemophilia?

Before modern-day drugs, she would probably have had difficulty surviving puberty when she began monthly menstruation. Modern day drugs can provide considerable assistance to those with hemophilia and improve their chances of living a relatively normal life.
Asemmisa {{asɛmmisaAhyɛnsode}}
7.

The next generation of the present British royal family--William and Harry--are carriers for hemophilia.

If a male has the hemophilia gene on his "X" chromosome then it is expressed and he has hemophilia. William and Harry's squares are not shaded in on the pedigree chart so they don't have hemophilia.
Asemmisa {{asɛmmisaAhyɛnsode}}
8.

The sex chromosome(s) in male mammal's gametes (sperm) is/are

Asemmisa {{asɛmmisaAhyɛnsode}}
9.

The sex chromosome(s) in a female mammal's gamete (egg) is/are

Asemmisa {{asɛmmisaAhyɛnsode}}
10.

The half shaded in circles represents a